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Epidermal Growth Factor (EGF)

URG; Beta-Urogastrone; Pro-epidermal growth factor

Epidermal growth factor (EGF) was discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice.EGF is a member of a family of growth factors that bind to the same 170 kDa receptor, including TGF-, vaccinia growth factor and amphiregulin. EGF is initially synthesized as a large (130 kDa) precursor molecule in which the mature, soluble EGF sequence (6 kDa) is located. The precursor, which functions as a source for soluble EGF, may also have a role in mediation of intercellular communication between cells displaying pro-EGF on their surfaces and cells with EGF receptors.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W250Hu01 Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
PW250Hu01 Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
LW250Hu71 Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits KEW250Hu ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
KCW250Hu CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W250Mu01 Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
PW250Mu01 Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits KEW250Mu ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
KCW250Mu CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W250Ra01 Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies MW250Ra21 Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
PW250Ra01 Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
LW250Ra72 Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits KEW250Ra ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
KCW250Ra CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W250Ca01 Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
PW250Ca01 Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
LW250Ca71 Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W250Po01 Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies MW250Po21 Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
PW250Po01 Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
LW250Po71 Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
LW250Po81 FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits KEW250Po ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
PW250Bo01 Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
LW250Bo71 Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Epidermal Growth Factor (EGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Epidermal Growth Factor (EGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Epidermal Growth Factor (EGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Epidermal Growth Factor (EGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Epidermal Growth Factor (EGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Epidermal Growth Factor (EGF) CLIA assay for Antigen Detection

Reference

"Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization."
Nucleic Acids Res. 14:8427-8446(1986) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The primary structure of human urogastrone."
Int. J. Pept. Protein Res. 9:107-118(1977) [PubMed] [Europe PMC] [Abstract]

"The primary structure of human EGF produced by genetic engineering, studied by high-performance tandem mass spectrometry."
Biochem. Biophys. Res. Commun. 163:1100-1106(1989) [PubMed] [Europe PMC] [Abstract]

"Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD."
Mol. Cell. Proteomics 0:0-0(2011) [PubMed] [Europe PMC] [Abstract]

"Human epidermal growth factor. High resolution solution structure and comparison with human transforming growth factor alpha."
J. Mol. Biol. 227:271-282(1992) [PubMed] [Europe PMC] [Abstract]

"Neurotrophic actions of a novel molluscan epidermal growth factor."
J. Neurosci. 20:6355-6364(2000) [PubMed] [Europe PMC] [Abstract]

"Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia."
J. Clin. Invest. 117:2260-2267(2007) [PubMed] [Europe PMC] [Abstract]

"Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling."
Cell 145:79-91(2011) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of human epidermal growth factor and its dimerization."
J. Biol. Chem. 276:34913-34917(2001) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains."
Cell 110:775-787(2002) [PubMed] [Europe PMC] [Abstract]

"EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization."
Mol. Cell 11:507-517(2003) [PubMed] [Europe PMC] [Abstract]

"The NMR solution structure of human epidermal growth factor (hEGF) at physiological pH and its interactions with suramin."
Biochem. Biophys. Res. Commun. 402:705-710(2010) [PubMed] [Europe PMC] [Abstract]

"Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor."
Mol. Cell. Biol. 30:5432-5443(2010) [PubMed] [Europe PMC] [Abstract]