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Vinculin (VCL)
Vinculin (VCL)
MVCL; Metavinculin
In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Its sequence is 20-30% homologous to alpha-catenin, which serves a similar function.
Vinculin is a 117 kDa cytoskeletal protein with 1066 amino acids. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. Vinculin consists of a globular head domain that contains binding sites for talin and alpha-actinin as well as a tyrosine phosphorylation site, while the tail region contains binding sites for F-actin, paxillin and lipids.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
V002Mu01
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
PV002Mu01
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
KEV002Mu
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Vinculin (VCL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Vinculin (VCL) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Vinculin (VCL) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Vinculin (VCL) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Vinculin (VCL) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Vinculin (VCL) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Vinculin (VCL) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Vinculin (VCL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Vinculin (VCL) CLIA assay for Antigen Detection
Reference
"Complete sequence of human vinculin and assignment of the gene to chromosome 10." Proc. Natl. Acad. Sci. U.S.A. 87:5667-5671(1990) [PubMed ] [Europe PMC ] [Abstract ]
"The full-ORF clone resource of the German cDNA consortium." BMC Genomics 8:399-399(2007) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Organization of the human gene encoding the cytoskeletal protein vinculin and the sequence of the vinculin promoter." PubMed ] [Europe PMC ] [Abstract ]
