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Angiopoietin 1 (ANGPT1)

ANG1; AGP1; AGPT; ANG-I

Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin 1 has been shown to interact with TEK tyrosine kinase. Angiopoietin1 (Ang1) is a novel angiogenic factor with important actions on endothelial cell (EC) differentiation and vascular maturation. Ang1 has been shown to prevent EC apoptosis through activation of PI3-kinase/Akt, a pathway that is also known to activate endothelium nitric oxide synthase (eNOS).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W697Hu01 Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies MW697Hu21 Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
PW697Hu01 Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
LW697Hu71 Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits KEW697Hu ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W697Mu01 Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
PW697Mu01 Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
LW697Mu71 Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits KEW697Mu ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W697Ra01 Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies MW697Ra21 Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
PW697Ra01 Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits KEW697Ra ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W697Ca01 Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
PW697Ca01 Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
LW697Ca71 Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits KEW697Ca ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W697Po01 Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
PW697Po01 Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W697Bo01 Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies MW697Bo21 Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
PW697Bo01 Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits KEW697Bo ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W697Ga01 Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
PW697Ga01 Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Angiopoietin 1 (ANGPT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Angiopoietin 1 (ANGPT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Angiopoietin 1 (ANGPT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Angiopoietin 1 (ANGPT1) CLIA assay for Antigen Detection

Reference

"Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning."
Cell 87:1161-1169(1996) [PubMed] [Europe PMC] [Abstract]

"Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1."
DNA Res. 1:27-35(1994) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 8."
Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]

"Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis."
Science 277:55-60(1997) [PubMed] [Europe PMC] [Abstract]

"Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats."
J. Biol. Chem. 278:1721-1727(2003) [PubMed] [Europe PMC] [Abstract]

"Biological characterization of angiopoietin-3 and angiopoietin-4."
FASEB J. 18:1200-1208(2004) [PubMed] [Europe PMC] [Abstract]

"Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1."
Nat. Cell Biol. 10:513-526(2008) [PubMed] [Europe PMC] [Abstract]

"Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts."
Nat. Cell Biol. 10:527-537(2008) [PubMed] [Europe PMC] [Abstract]

"Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system."
Nat. Rev. Mol. Cell Biol. 10:165-177(2009) [PubMed] [Europe PMC] [Abstract]

"Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis."
Histol. Histopathol. 25:387-396(2010) [PubMed] [Europe PMC] [Abstract]

"Targeting the ANGPT-TIE2 pathway in malignancy."
Nat. Rev. Cancer 10:575-585(2010) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]