Erythropoietin (EPO)
EP; Epoetin; Erythropoetin; Hematopoietin; Hemopoietin
Erythropoietin is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow.Also called hematopoietin or hemopoietin, it is produced by the peritubular capillary endothelial cells in the kidney, and is the hormone that regulates red blood cell production.
It also has other known biological functions. For example, erythropoietin plays an important role in the brain's response to neuronal injury.EPO is also involved in the wound healing process.When exogenous EPO is used as a performance-enhancing drug, it is classified as an erythropoiesis-stimulating agent (ESA). Exogenous EPO can often be detected in blood, due to slight difference from the endogenous protein, for example in features of posttranslational modification.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW678Hu01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW678Hu01 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAW678Hu01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW678Hu01 | CLIA Kit for Erythropoietin (EPO) | CLIA assay for Antigen Detection |
ELW678Hu01 | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW678Mu01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW678Mu01 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAW678Mu01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW678Mu01 | CLIA Kit for Erythropoietin (EPO) | CLIA assay for Antigen Detection |
ELW678Mu01 | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW678Ra01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW678Ra01 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAW678Ra01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW678Ra01 | CLIA Kit for Erythropoietin (EPO) | CLIA assay for Antigen Detection |
ELW678Ra01 | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW678Ca01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW678Ca01 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAW678Ca01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW678Ca01 | CLIA Kit for Erythropoietin (EPO) | CLIA assay for Antigen Detection |
ELW678Ca01 | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW678Po01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW678Po01 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAW678Po01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW678Po01 | CLIA Kit for Erythropoietin (EPO) | CLIA assay for Antigen Detection |
ELW678Po01 | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW678Bo01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW678Bo01 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAW678Bo01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW678Bo01 | CLIA Kit for Erythropoietin (EPO) | CLIA assay for Antigen Detection |
ELW678Bo01 | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW678Rb01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW678Rb01 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAW678Rb01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW678Rb01 | CLIA Kit for Erythropoietin (EPO) | CLIA assay for Antigen Detection |
ELW678Rb01 | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW678Mo01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW678Mo01 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAW678Mo01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IF. | |
Assay Kits | CLW678Mo01 | CLIA Kit for Erythropoietin (EPO) | CLIA assay for Antigen Detection |
ELW678Mo01 | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Nature 313:806-810(1985) [PubMed] [Europe PMC] [Abstract]
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Biochemistry 27:8618-8626(1988) [PubMed] [Europe PMC] [Abstract]
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Blood 98:3626-3634(2001) [PubMed] [Europe PMC] [Abstract]
"Efficiency of signalling through cytokine receptors depends critically on receptor orientation."
Nature 395:511-516(1998) [PubMed] [Europe PMC] [Abstract]
"NMR structure of human erythropoietin and a comparison with its receptor bound conformation."
Nat. Struct. Biol. 5:861-866(1998) [PubMed] [Europe PMC] [Abstract]
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Proc. Natl. Acad. Sci. U.S.A. 105:6998-7003(2008) [PubMed] [Europe PMC] [Abstract]