Fibroblast Growth Factor 4 (FGF4)
HBGF4; HST; HSTF1; KFGF; K-FGF; Heparin Secretory Transforming Protein 1; Kaposi Sarcoma Oncogene; Transforming Protein KS3; FGF-Related Oncogene
Fibroblast growth factor 4 is a protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity.
This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW672Hu01 | Recombinant Fibroblast Growth Factor 4 (FGF4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW672Hu01 | Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IP. |
| PAW672Hu01 | Polyclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW672Hu01 | CLIA Kit for Fibroblast Growth Factor 4 (FGF4) | CLIA assay for Antigen Detection |
| ELW672Hu01 | ELISA Kit for Fibroblast Growth Factor 4 (FGF4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW672Mu01 | Recombinant Fibroblast Growth Factor 4 (FGF4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW672Mu01 | Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IP. |
| PAW672Mu01 | Polyclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW672Mu01 | CLIA Kit for Fibroblast Growth Factor 4 (FGF4) | CLIA assay for Antigen Detection |
| ELW672Mu01 | ELISA Kit for Fibroblast Growth Factor 4 (FGF4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW672Ra01 | Recombinant Fibroblast Growth Factor 4 (FGF4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW672Ra01 | Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IP. |
| PAW672Ra01 | Polyclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW672Ra01 | CLIA Kit for Fibroblast Growth Factor 4 (FGF4) | CLIA assay for Antigen Detection |
| ELW672Ra01 | ELISA Kit for Fibroblast Growth Factor 4 (FGF4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW672Ca01 | Recombinant Fibroblast Growth Factor 4 (FGF4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW672Ca01 | Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IP. |
| PAW672Ca01 | Polyclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW672Ca01 | CLIA Kit for Fibroblast Growth Factor 4 (FGF4) | CLIA assay for Antigen Detection |
| ELW672Ca01 | ELISA Kit for Fibroblast Growth Factor 4 (FGF4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW672Po01 | Recombinant Fibroblast Growth Factor 4 (FGF4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW672Po01 | Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IP. |
| PAW672Po01 | Polyclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW672Po01 | CLIA Kit for Fibroblast Growth Factor 4 (FGF4) | CLIA assay for Antigen Detection |
| ELW672Po01 | ELISA Kit for Fibroblast Growth Factor 4 (FGF4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW672Bo01 | Recombinant Fibroblast Growth Factor 4 (FGF4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW672Bo01 | Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IP. |
| PAW672Bo01 | Polyclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW672Bo01 | CLIA Kit for Fibroblast Growth Factor 4 (FGF4) | CLIA assay for Antigen Detection |
| ELW672Bo01 | ELISA Kit for Fibroblast Growth Factor 4 (FGF4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW672Rb01 | Recombinant Fibroblast Growth Factor 4 (FGF4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW672Rb01 | Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IP. |
| PAW672Rb01 | Polyclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW672Rb01 | CLIA Kit for Fibroblast Growth Factor 4 (FGF4) | CLIA assay for Antigen Detection |
| ELW672Rb01 | ELISA Kit for Fibroblast Growth Factor 4 (FGF4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW672Mo01 | Recombinant Fibroblast Growth Factor 4 (FGF4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW672Mo01 | Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IP. |
| PAW672Mo01 | Polyclonal Antibody to Fibroblast Growth Factor 4 (FGF4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW672Mo01 | CLIA Kit for Fibroblast Growth Factor 4 (FGF4) | CLIA assay for Antigen Detection |
| ELW672Mo01 | ELISA Kit for Fibroblast Growth Factor 4 (FGF4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal."
Stem Cells 26:767-774(2008) [PubMed] [Europe PMC] [Abstract]
"Genomic sequence of hst, a transforming gene encoding a protein homologous to fibroblast growth factors and the int-2-encoded protein."
Proc. Natl. Acad. Sci. U.S.A. 84:7305-7309(1987) [PubMed] [Europe PMC] [Abstract]
"cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity."
Proc. Natl. Acad. Sci. U.S.A. 84:2980-2984(1987) [PubMed] [Europe PMC] [Abstract]
"An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family."
Cell 50:729-737(1987) [PubMed] [Europe PMC] [Abstract]
"Receptor specificity of the fibroblast growth factor family."
J. Biol. Chem. 271:15292-15297(1996) [PubMed] [Europe PMC] [Abstract]
"Fibroblast growth factor signalling: from development to cancer."
Nat. Rev. Cancer 10:116-129(2010) [PubMed] [Europe PMC] [Abstract]
"Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis."
Mol. Cell. Biol. 21:5946-5957(2001) [PubMed] [Europe PMC] [Abstract]