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Interferon Gamma (IFNg)

IFN-G; IFG; IFI; INFr; IFN, Immune Interferon

Interferon gamma (IFN-gama ) is a multifunctional protein first observed as an antiviral activity in cultures of Sindbis virus-infected leukocytes stimulated by PHA . Produced by T lymphocytes and natural killer (NK) cells, IFN-γ is now known to be both an inhibitor of viral replication and a regulator of numerous immunological functions.

IFN-γ influences the class of antibody produced by B cells, upregulates class I and II MHC complex antigens and increases. the efficiency of macrophage-mediated killing of intracellular parasites. Most of the activities attributed to IFN-γ are believed to be mediated by IFN-γ-induced proteins. The appearance of such proteins is a consequence of IFN-γ binding to a specific receptor that is distinct from the receptor for IFN-αandβ.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Hu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Hu22 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Hu01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
LW658Hu71 Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
LW658Hu81 FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Hu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Hu CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Mu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Mu21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Mu01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
LW658Mu71 Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
LW658Mu81 FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Mu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Mu CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Ra01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Ra21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Ra01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
LW658Ra71 Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
LW658Ra81 FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Ra ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Ra CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Ca01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Ca21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Ca01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Ca ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Ca CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Po01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Po21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Po01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Po ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Po CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Bo01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Bo21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Bo01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Bo ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Bo CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Si01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Si21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Si01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Si ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Si CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Ga01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Ga21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Ga01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
LW658Ga71 Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Ga ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Ga CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Ov01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Ov21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Ov01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
LW658Ov71 Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
LW658Ov81 FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Rb01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Rb21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Rb51 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
LW658Rb71 Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
LW658Rb81 FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Rb ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Rb CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Gu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Gu21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Gu01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
LW658Gu71 Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
LW658Gu91 HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Gu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
KCW658Gu CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W658Eq01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies MW658Eq21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PW658Eq01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits KEW658Eq ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Gamma (IFNg) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Gamma (IFNg) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Gamma (IFNg) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Gamma (IFNg) CLIA assay for Antigen Detection

Reference

"Structure of the human immune interferon gene."
Nature 298:859-863(1982) [PubMed] [Europe PMC] [Abstract]

"Expression of human immune interferon cDNA in E. coli and monkey cells."
Nature 295:503-508(1982) [PubMed] [Europe PMC] [Abstract]

"Cloning and expression of a novel variant of human interferon-gamma cDNA."
J. Biochem. 97:153-159(1985) [PubMed] [Europe PMC] [Abstract]

"Cloning and structure of the human immune interferon-gamma chromosomal gene."
EMBO J. 1:953-958(1982) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells."
Nucleic Acids Res. 10:2487-2501(1982) [PubMed] [Europe PMC] [Abstract]

"Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation."
J. Biol. Chem. 259:6790-6797(1984) [PubMed] [Europe PMC] [Abstract]

"Structural characterization of human interferon gamma. Heterogeneity of the carboxyl terminus."
Eur. J. Biochem. 166:145-149(1987) [PubMed] [Europe PMC] [Abstract]

"Studies on the sugar chains of interferon-gamma from human peripheral-blood lymphocytes."
J. Biochem. 105:1034-1039(1989) [PubMed] [Europe PMC] [Abstract]

"Three-dimensional structure of recombinant human interferon-gamma."
Science 252:698-702(1991) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor."
Nature 376:230-235(1995) [PubMed] [Europe PMC] [Abstract]

"Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma."
J. Mol. Biol. 299:169-179(2000) [PubMed] [Europe PMC] [Abstract]

"Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex."
Structure 8:927-936(2000) [PubMed] [Europe PMC] [Abstract]

"1H, 13C, and 15N NMR backbone assignments and secondary structure of human interferon-gamma."
Biochemistry 31:8180-8190(1992) [PubMed] [Europe PMC] [Abstract]

"Homozygosis for (12) CA repeats in the first intron of the human IFN-gamma gene is significantly associated with the risk of aplastic anaemia in Caucasian population."
Br. J. Haematol. 126:682-685(2004) [PubMed] [Europe PMC] [Abstract]