Insulin Like Growth Factor Binding Protein 2 (IGFBP2)
IBP2; IGF-BP53
Insulin-like growth factor binding protein-2 (IGFBP-2) is one of six characterized IGFBPs which specifically bind and modulate the actions of IGF-I and IGF-II. The binding affinity of IGFBP-2 for IGF-II is estimated to be significantly higher than for IGF-I, suggesting a role in regulation of IGF-II action. Studies in the fetal sheep indicate that IGFBP-2 is produced in many tissues, apparently coincident with IGF-II expression.
Recent studies of serum IGFBP-2 levels have shown that, unlike for IGFBP-1, there is negligible variability during the day and, unlike IGFBP-1 and IGFBP-3, virtually no change during puberty. IGFBP-2 has also been identified in other body fluids such as cerebrospinal, amniotic and coelomic fluids, urine and seminal fluid.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW654Hu01 | Recombinant Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW654Hu01 | Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IP. |
PAW654Hu01 | Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IF. | |
Assay Kits | CLW654Hu01 | CLIA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | CLIA assay for Antigen Detection |
ELW654Hu01 | ELISA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW654Mu01 | Recombinant Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW654Mu01 | Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IP. |
PAW654Mu01 | Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IF. | |
Assay Kits | CLW654Mu01 | CLIA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | CLIA assay for Antigen Detection |
ELW654Mu01 | ELISA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW654Ra01 | Recombinant Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW654Ra01 | Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IP. |
PAW654Ra01 | Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IF. | |
Assay Kits | CLW654Ra01 | CLIA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | CLIA assay for Antigen Detection |
ELW654Ra01 | ELISA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW654Ca01 | Recombinant Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW654Ca01 | Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IP. |
PAW654Ca01 | Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IF. | |
Assay Kits | CLW654Ca01 | CLIA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | CLIA assay for Antigen Detection |
ELW654Ca01 | ELISA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW654Po01 | Recombinant Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW654Po01 | Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IP. |
PAW654Po01 | Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IF. | |
Assay Kits | CLW654Po01 | CLIA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | CLIA assay for Antigen Detection |
ELW654Po01 | ELISA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW654Bo01 | Recombinant Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW654Bo01 | Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IP. |
PAW654Bo01 | Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IF. | |
Assay Kits | CLW654Bo01 | CLIA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | CLIA assay for Antigen Detection |
ELW654Bo01 | ELISA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW654Rb01 | Recombinant Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW654Rb01 | Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IP. |
PAW654Rb01 | Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IF. | |
Assay Kits | CLW654Rb01 | CLIA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | CLIA assay for Antigen Detection |
ELW654Rb01 | ELISA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW654Mo01 | Recombinant Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW654Mo01 | Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IP. |
PAW654Mo01 | Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | WB; IHC; ICC; IF. | |
Assay Kits | CLW654Mo01 | CLIA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | CLIA assay for Antigen Detection |
ELW654Mo01 | ELISA Kit for Insulin Like Growth Factor Binding Protein 2 (IGFBP2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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EMBO J. 8:2497-2502(1989) [PubMed] [Europe PMC] [Abstract]
"Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia."
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PLoS ONE 3:E3926-E3926(2008) [PubMed] [Europe PMC] [Abstract]
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J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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J. Mol. Biol. 364:690-704(2006) [PubMed] [Europe PMC] [Abstract]