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Interleukin 12A (IL12A)
Interleukin 12A (IL12A)
p35; IL12-A; CLMF1; NFSK; NKSF1; Natural Killer Cell Stimulatory Factor 1; Cytotoxic Lymphocyte Maturation Factor 1; NF Cell Stimulatory Factor Chain 1
Interleukin 12A also known as IL12A encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family.
This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W648Mu01
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
PW648Mu01
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
LW648Mu71
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
KEW648Mu
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W648Ra01
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
MW648Ra21
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
PW648Ra01
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
KEW648Ra
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W648Ca01
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
MW648Ca21
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
PW648Ca01
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
KEW648Ca
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W648Po01
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
MW648Po21
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
PW648Po01
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
KEW648Po
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W648Bo01
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
MW648Bo21
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
PW648Bo01
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
KEW648Bo
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W648Ga01
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
MW648Ga21
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
PW648Ga01
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
KEW648Ga
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W648Eq01
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
MW648Eq21
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
PW648Eq01
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
KEW648Eq
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W648Cp01
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
MW648Cp21
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
PW648Cp01
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
KEW648Cp
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 12A (IL12A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 12A (IL12A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 12A (IL12A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 12A (IL12A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 12A (IL12A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 12A (IL12A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 12A (IL12A) CLIA assay for Antigen Detection
Reference
"Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells." PubMed ] [Europe PMC ] [Abstract ]
"Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor." Proc. Natl. Acad. Sci. U.S.A. 88:4143-4147(1991) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells." Proc. Natl. Acad. Sci. U.S.A. 87:6808-6812(1990) [PubMed ] [Europe PMC ] [Abstract ]
"Sequence similarity between NKSF and the IL-6/G-CSF family." Immunol. Today 13:77-78(1992) [PubMed ] [Europe PMC ] [Abstract ]
"Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection." Cell. Microbiol. 8:565-580(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12." EMBO J. 19:3530-3541(2000) [PubMed ] [Europe PMC ] [Abstract ]
