Interleukin 1 Alpha (IL1a)
IL1-A; IL-1α; IL1F1; Preinterleukin 1 Alpha; Hematopoietin-1; Pro-Interleukin-1-Alpha; Interleukin-1 Family Member 1
IL-1α is a member of interleukin 1 family. IL-1α and IL-1β recognize the same IL-1 receptor and share a number of similar biological functions. IL-1α is predominantly a cell-associated molecule whereas IL-1β is a secreted molecule.
IL-1α is synthesized primarily as a 31 kDa precursor that lacks a signal peptide. Cleavage of the precursor is via the cysteine protease calpain, resulting in a 17.5 kDa mature IL-1 molecule. Being active in the processed form, the IL-1 precursor is also biologically active via specific cell binding. A portion of the precursor is transported to the cell surface and associated with the cell membrane. Precursor IL-1α can be released and cleaved by extracellular proteases when the cells die, and can also be cleaved by activation of the calcium-dependent, membrane-associated calpains.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW636Hu01 | Recombinant Interleukin 1 Alpha (IL1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW636Hu01 | Monoclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IP. |
| PAW636Hu01 | Polyclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW636Hu01 | CLIA Kit for Interleukin 1 Alpha (IL1a) | CLIA assay for Antigen Detection |
| ELW636Hu01 | ELISA Kit for Interleukin 1 Alpha (IL1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW636Mu01 | Recombinant Interleukin 1 Alpha (IL1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW636Mu01 | Monoclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IP. |
| PAW636Mu01 | Polyclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW636Mu01 | CLIA Kit for Interleukin 1 Alpha (IL1a) | CLIA assay for Antigen Detection |
| ELW636Mu01 | ELISA Kit for Interleukin 1 Alpha (IL1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW636Ra01 | Recombinant Interleukin 1 Alpha (IL1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW636Ra01 | Monoclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IP. |
| PAW636Ra01 | Polyclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW636Ra01 | CLIA Kit for Interleukin 1 Alpha (IL1a) | CLIA assay for Antigen Detection |
| ELW636Ra01 | ELISA Kit for Interleukin 1 Alpha (IL1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW636Ca01 | Recombinant Interleukin 1 Alpha (IL1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW636Ca01 | Monoclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IP. |
| PAW636Ca01 | Polyclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW636Ca01 | CLIA Kit for Interleukin 1 Alpha (IL1a) | CLIA assay for Antigen Detection |
| ELW636Ca01 | ELISA Kit for Interleukin 1 Alpha (IL1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW636Po01 | Recombinant Interleukin 1 Alpha (IL1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW636Po01 | Monoclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IP. |
| PAW636Po01 | Polyclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW636Po01 | CLIA Kit for Interleukin 1 Alpha (IL1a) | CLIA assay for Antigen Detection |
| ELW636Po01 | ELISA Kit for Interleukin 1 Alpha (IL1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW636Bo01 | Recombinant Interleukin 1 Alpha (IL1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW636Bo01 | Monoclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IP. |
| PAW636Bo01 | Polyclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW636Bo01 | CLIA Kit for Interleukin 1 Alpha (IL1a) | CLIA assay for Antigen Detection |
| ELW636Bo01 | ELISA Kit for Interleukin 1 Alpha (IL1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW636Rb01 | Recombinant Interleukin 1 Alpha (IL1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW636Rb01 | Monoclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IP. |
| PAW636Rb01 | Polyclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW636Rb01 | CLIA Kit for Interleukin 1 Alpha (IL1a) | CLIA assay for Antigen Detection |
| ELW636Rb01 | ELISA Kit for Interleukin 1 Alpha (IL1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW636Mo01 | Recombinant Interleukin 1 Alpha (IL1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW636Mo01 | Monoclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IP. |
| PAW636Mo01 | Polyclonal Antibody to Interleukin 1 Alpha (IL1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW636Mo01 | CLIA Kit for Interleukin 1 Alpha (IL1a) | CLIA assay for Antigen Detection |
| ELW636Mo01 | ELISA Kit for Interleukin 1 Alpha (IL1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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