Call Now

Leukemia Inhibitory Factor (LIF)

CDF; D-FACTOR; HILDA; MLPLI; Cholinergic Differentiation Factor; Differentiation-Stimulating Factor; Melanoma-Derived LPL Inhibitor; Emfilermin

Leukemia inhibitory factor, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukaemic cells. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.

LIF is normally expressed in the trophectoderm of the developing embryo, with its receptor LIFR expressed throughout the inner cell mass. As embryonic stem cells are derived from the inner cell mass at the blastocyst stage, removing them from the inner cell mass also removes their source of LIF.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W625Hu01 Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies MW625Hu22 Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
PW625Hu01 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits KEW625Hu ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W625Mu01 Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
PW625Mu01 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W625Ra01 Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies MW625Ra21 Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
PW625Ra01 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits KEW625Ra ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W625Ca01 Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
PW625Ca01 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W625Po01 Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies MW625Po21 Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
PW625Po01 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits KEW625Po ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W625Bo01 Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
PW625Bo01 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits KEW625Bo ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W625Cp01 Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
PW625Cp01 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Leukemia Inhibitory Factor (LIF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Leukemia Inhibitory Factor (LIF) Bioactivity
Antibodies NONE Monoclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Leukemia Inhibitory Factor (LIF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Leukemia Inhibitory Factor (LIF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Leukemia Inhibitory Factor (LIF) CLIA assay for Antigen Detection

Reference

"Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells."
Nature 336:690-692(1988) [PubMed] [Europe PMC] [Abstract]

"Genomic cloning and heterologous expression of human differentiation-stimulating factor."
DNA 8:351-359(1989) [PubMed] [Europe PMC] [Abstract]

"Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation."
Nat. Biotechnol. 22:707-716(2004) [PubMed] [Europe PMC] [Abstract]

"Structural organization of the genes for murine and human leukemia inhibitory factor. Evolutionary conservation of coding and non-coding regions."
J. Biol. Chem. 265:8833-8841(1990) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 22."
Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor."
Proc. Natl. Acad. Sci. U.S.A. 85:2623-2627(1988) [PubMed] [Europe PMC] [Abstract]

"Purification of a lipoprotein lipase-inhibiting protein produced by a melanoma cell line associated with cancer cachexia."
Biochem. Biophys. Res. Commun. 160:1085-1092(1989) [PubMed] [Europe PMC] [Abstract]

"Glycosylation pattern and disulfide assignments of recombinant human differentiation-stimulating factor."
Arch. Biochem. Biophys. 302:484-489(1993) [PubMed] [Europe PMC] [Abstract]

"Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130."
Mol. Cell 12:577-589(2003) [PubMed] [Europe PMC] [Abstract]

"An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor."
Proc. Natl. Acad. Sci. U.S.A. 104:12737-12742(2007) [PubMed] [Europe PMC] [Abstract]