Monocyte Chemotactic Protein 3 (MCP3)
CCL7; FIC; MARC; NC28; MCP3; SCYA7; Chemokine C-C-Motif Ligand 7; Small Inducible Cytokine A7; Monocyte Chemoattractant Protein 3
Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). Due to CCL7 possessing two adjacent N-terminal cysteine residues in its mature protein, it is classified among the subfamily of chemokines known as CC chemokines.
The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. CCL7 is one of the most pluripotent chemokines, produced by certain tumor cell lines and by macrophages and acting on multiple cell types including monocytes, lymphocytes, eosinophils, basophils, dendritic cells, and natural killer cells.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW621Hu01 | Recombinant Monocyte Chemotactic Protein 3 (MCP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW621Hu01 | Monoclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IP. |
| PAW621Hu01 | Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW621Hu01 | CLIA Kit for Monocyte Chemotactic Protein 3 (MCP3) | CLIA assay for Antigen Detection |
| ELW621Hu01 | ELISA Kit for Monocyte Chemotactic Protein 3 (MCP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW621Mu01 | Recombinant Monocyte Chemotactic Protein 3 (MCP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW621Mu01 | Monoclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IP. |
| PAW621Mu01 | Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW621Mu01 | CLIA Kit for Monocyte Chemotactic Protein 3 (MCP3) | CLIA assay for Antigen Detection |
| ELW621Mu01 | ELISA Kit for Monocyte Chemotactic Protein 3 (MCP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW621Ra01 | Recombinant Monocyte Chemotactic Protein 3 (MCP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW621Ra01 | Monoclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IP. |
| PAW621Ra01 | Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW621Ra01 | CLIA Kit for Monocyte Chemotactic Protein 3 (MCP3) | CLIA assay for Antigen Detection |
| ELW621Ra01 | ELISA Kit for Monocyte Chemotactic Protein 3 (MCP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW621Ca01 | Recombinant Monocyte Chemotactic Protein 3 (MCP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW621Ca01 | Monoclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IP. |
| PAW621Ca01 | Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW621Ca01 | CLIA Kit for Monocyte Chemotactic Protein 3 (MCP3) | CLIA assay for Antigen Detection |
| ELW621Ca01 | ELISA Kit for Monocyte Chemotactic Protein 3 (MCP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW621Po01 | Recombinant Monocyte Chemotactic Protein 3 (MCP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW621Po01 | Monoclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IP. |
| PAW621Po01 | Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW621Po01 | CLIA Kit for Monocyte Chemotactic Protein 3 (MCP3) | CLIA assay for Antigen Detection |
| ELW621Po01 | ELISA Kit for Monocyte Chemotactic Protein 3 (MCP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW621Bo01 | Recombinant Monocyte Chemotactic Protein 3 (MCP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW621Bo01 | Monoclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IP. |
| PAW621Bo01 | Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW621Bo01 | CLIA Kit for Monocyte Chemotactic Protein 3 (MCP3) | CLIA assay for Antigen Detection |
| ELW621Bo01 | ELISA Kit for Monocyte Chemotactic Protein 3 (MCP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW621Rb01 | Recombinant Monocyte Chemotactic Protein 3 (MCP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW621Rb01 | Monoclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IP. |
| PAW621Rb01 | Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW621Rb01 | CLIA Kit for Monocyte Chemotactic Protein 3 (MCP3) | CLIA assay for Antigen Detection |
| ELW621Rb01 | ELISA Kit for Monocyte Chemotactic Protein 3 (MCP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW621Mo01 | Recombinant Monocyte Chemotactic Protein 3 (MCP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW621Mo01 | Monoclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IP. |
| PAW621Mo01 | Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW621Mo01 | CLIA Kit for Monocyte Chemotactic Protein 3 (MCP3) | CLIA assay for Antigen Detection |
| ELW621Mo01 | ELISA Kit for Monocyte Chemotactic Protein 3 (MCP3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Human monocyte chemotactic protein-3 (MCP-3): molecular cloning of the cDNA and comparison with other chemokines."
Biochem. Biophys. Res. Commun. 191:535-542(1993) [PubMed] [Europe PMC] [Abstract]
"The human MCP-3 gene (SCYA7): cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17q11.2-q12."
Genomics 21:403-408(1994) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning of the MCP-3 chemokine gene and regulation of its expression."
Eur. Cytokine Netw. 4:99-110(1993) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Structural and functional identification of two human, tumor-derived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family."
J. Exp. Med. 176:59-65(1992) [PubMed] [Europe PMC] [Abstract]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
"Structural characterization of a monomeric chemokine: monocyte chemoattractant protein-3."
FEBS Lett. 395:277-282(1996) [PubMed] [Europe PMC] [Abstract]
"Determination of the three-dimensional structure of CC chemokine monocyte chemoattractant protein 3 by 1H two-dimensional NMR spectroscopy."
Biochemistry 36:4412-4422(1997) [PubMed] [Europe PMC] [Abstract]
, Submitted (AUG-1998) to the PDB data bank