Macrophage Inflammatory Protein 3 Alpha (MIP3a)
CCL20; CKb4; LARC; MIP3-A; SCYA20; ST38; Small Inducible Cytokine Subfamily A(Cys-Cys)Member 20; Beta-Chemokine Exodus-1; Liver And Activation-Regulated Chemokine
Chemokine (C-C motif) ligand 20 is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils.CCL20 is implicated in the formation and function of mucosal lymphoid tissues via chemoattraction of lymphocytes and dendritic cells towards the epithelial cells surrounding these tissues.
CCL20 elicits its effects on its target cells by binding and activating the chemokine receptor CCR6.CCL20 can be induced by microbial factors such as lipopolysaccharide, and inflammatory cytokines such as tumor necrosis factor and interferon-γ, and down-regulated by IL-10. CCL20 is expressed in several tissues with highest expression observed in peripheral blood lymphocytes, lymph nodes, liver, appendix, and fetal lung and lower levels in thymus, testis, prostate and gut.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW615Hu01 | Recombinant Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW615Hu01 | Monoclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IP. |
PAW615Hu01 | Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IF. | |
Assay Kits | CLW615Hu01 | CLIA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | CLIA assay for Antigen Detection |
ELW615Hu01 | ELISA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW615Mu01 | Recombinant Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW615Mu01 | Monoclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IP. |
PAW615Mu01 | Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IF. | |
Assay Kits | CLW615Mu01 | CLIA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | CLIA assay for Antigen Detection |
ELW615Mu01 | ELISA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW615Ra01 | Recombinant Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW615Ra01 | Monoclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IP. |
PAW615Ra01 | Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IF. | |
Assay Kits | CLW615Ra01 | CLIA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | CLIA assay for Antigen Detection |
ELW615Ra01 | ELISA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW615Ca01 | Recombinant Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW615Ca01 | Monoclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IP. |
PAW615Ca01 | Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IF. | |
Assay Kits | CLW615Ca01 | CLIA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | CLIA assay for Antigen Detection |
ELW615Ca01 | ELISA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW615Po01 | Recombinant Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW615Po01 | Monoclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IP. |
PAW615Po01 | Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IF. | |
Assay Kits | CLW615Po01 | CLIA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | CLIA assay for Antigen Detection |
ELW615Po01 | ELISA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW615Bo01 | Recombinant Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW615Bo01 | Monoclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IP. |
PAW615Bo01 | Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IF. | |
Assay Kits | CLW615Bo01 | CLIA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | CLIA assay for Antigen Detection |
ELW615Bo01 | ELISA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW615Rb01 | Recombinant Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW615Rb01 | Monoclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IP. |
PAW615Rb01 | Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IF. | |
Assay Kits | CLW615Rb01 | CLIA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | CLIA assay for Antigen Detection |
ELW615Rb01 | ELISA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW615Mo01 | Recombinant Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW615Mo01 | Monoclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IP. |
PAW615Mo01 | Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a) | WB; IHC; ICC; IF. | |
Assay Kits | CLW615Mo01 | CLIA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | CLIA assay for Antigen Detection |
ELW615Mo01 | ELISA Kit for Macrophage Inflammatory Protein 3 Alpha (MIP3a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta."
J. Immunol. 158:1033-1036(1997) [PubMed] [Europe PMC] [Abstract]
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Blood 89:3315-3322(1997) [PubMed] [Europe PMC] [Abstract]
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Genomics 73:28-37(2001) [PubMed] [Europe PMC] [Abstract]
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Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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