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Matrix Metalloproteinase 7 (MMP7)

MPSL1; MAT; PUMP-1; Matrilysin Uterine; Matrilysin; Matrin; Pump-1 Protease; Uterine Metalloproteinase

SPN W608
HGNC 7174
MGI 103189
PubMed 22974215
RGD 3100
UniProt P09237
Wiki MMP7

MMP7, also known as Matrilysin, is the smallest member of the MMP-family, it is a zinc-dependent metalloproteinase and is overexpressed in colon cancer and many other human cancers. MMP7 is a secreted matrix metalloproteinase, which contributes to angiogenesis by breaking down basement membranes. Matrix Metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components.

MMP7 is responsible for hydrolyzing proteoglycans and ECM glycoproteins. It is expressed in normal cells, specifically glandular epithelial cells. MMP7, is thought to play an important role in the early steps of tumor progression. Expression of MMP2, MMP7 and MMP11 is greater in pancreatic carcinoma than in normal pancreas.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W608Hu01 Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies MW608Hu22 Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
PW608Hu01 Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits KEW608Hu ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
KCW608Hu CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W608Mu01 Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
PW608Mu01 Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits KEW608Mu ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
KCW608Mu CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W608Ra01 Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies MW608Ra21 Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
PW608Ra01 Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits KEW608Ra ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
KCW608Ra CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W608Bo01 Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies MW608Bo21 Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
PW608Bo01 Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits KEW608Bo ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
KCW608Bo CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W608Eq01 Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies MW608Eq21 Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
PW608Eq01 Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits KEW608Eq ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
KCW608Eq CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W608Cp01 Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies MW608Cp21 Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
PW608Cp01 Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits KEW608Cp ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
KCW608Cp CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 7 (MMP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 7 (MMP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 7 (MMP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 7 (MMP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 7 (MMP7) CLIA assay for Antigen Detection

Reference

"The collagenase gene family in humans consists of at least four members."
Biochem. J. 253:187-192(1988) [PubMed] [Europe PMC] [Abstract]

"Molecular characterization of a low-molecular-mass matrix metalloproteinase secreted by glomerular mesangial cells as PUMP-1."
Biochem. J. 285:899-905(1992) [PubMed] [Europe PMC] [Abstract]

"Structure and expression of the human gene for the matrix metalloproteinase matrilysin."
J. Biol. Chem. 269:2032-2040(1994) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line."
Cancer Res. 50:7758-7764(1990) [PubMed] [Europe PMC] [Abstract]

"Pump-1 cDNA codes for a protein with characteristics similar to those of classical collagenase family members."
Biochemistry 28:5327-5334(1989) [PubMed] [Europe PMC] [Abstract]

"Matrilysin-inhibitor complexes: common themes among metalloproteases."
Biochemistry 34:6602-6610(1995) [PubMed] [Europe PMC] [Abstract]

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