Cholecystokinin A Receptor (CCKAR)
CCK-A; CCK1; CCKRA; CCK1R; Cholecystokinin Type 1 Receptor
CCKAR is a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.Ulrich et al. (1993) used a combination of hybridization screening of a cDNA library and PCR to clone a 2.1-kb cDNA that encodes the human gallbladder CCK receptor type A (CCKAR). Nucleotide sequence analysis revealed an open reading frame encoding a 428-amino acid protein, with 7 putative transmembrane domains and a high degree of homology with the cholecystokinin A receptor protein of rat and guinea pig.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW606Hu01 | Recombinant Cholecystokinin A Receptor (CCKAR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW606Hu01 | Monoclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IP. |
| PAW606Hu01 | Polyclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW606Hu01 | CLIA Kit for Cholecystokinin A Receptor (CCKAR) | CLIA assay for Antigen Detection |
| ELW606Hu01 | ELISA Kit for Cholecystokinin A Receptor (CCKAR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW606Mu01 | Recombinant Cholecystokinin A Receptor (CCKAR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW606Mu01 | Monoclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IP. |
| PAW606Mu01 | Polyclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW606Mu01 | CLIA Kit for Cholecystokinin A Receptor (CCKAR) | CLIA assay for Antigen Detection |
| ELW606Mu01 | ELISA Kit for Cholecystokinin A Receptor (CCKAR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW606Ra01 | Recombinant Cholecystokinin A Receptor (CCKAR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW606Ra01 | Monoclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IP. |
| PAW606Ra01 | Polyclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW606Ra01 | CLIA Kit for Cholecystokinin A Receptor (CCKAR) | CLIA assay for Antigen Detection |
| ELW606Ra01 | ELISA Kit for Cholecystokinin A Receptor (CCKAR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW606Ca01 | Recombinant Cholecystokinin A Receptor (CCKAR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW606Ca01 | Monoclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IP. |
| PAW606Ca01 | Polyclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW606Ca01 | CLIA Kit for Cholecystokinin A Receptor (CCKAR) | CLIA assay for Antigen Detection |
| ELW606Ca01 | ELISA Kit for Cholecystokinin A Receptor (CCKAR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW606Po01 | Recombinant Cholecystokinin A Receptor (CCKAR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW606Po01 | Monoclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IP. |
| PAW606Po01 | Polyclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW606Po01 | CLIA Kit for Cholecystokinin A Receptor (CCKAR) | CLIA assay for Antigen Detection |
| ELW606Po01 | ELISA Kit for Cholecystokinin A Receptor (CCKAR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW606Bo01 | Recombinant Cholecystokinin A Receptor (CCKAR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW606Bo01 | Monoclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IP. |
| PAW606Bo01 | Polyclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW606Bo01 | CLIA Kit for Cholecystokinin A Receptor (CCKAR) | CLIA assay for Antigen Detection |
| ELW606Bo01 | ELISA Kit for Cholecystokinin A Receptor (CCKAR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW606Rb01 | Recombinant Cholecystokinin A Receptor (CCKAR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW606Rb01 | Monoclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IP. |
| PAW606Rb01 | Polyclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW606Rb01 | CLIA Kit for Cholecystokinin A Receptor (CCKAR) | CLIA assay for Antigen Detection |
| ELW606Rb01 | ELISA Kit for Cholecystokinin A Receptor (CCKAR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW606Mo01 | Recombinant Cholecystokinin A Receptor (CCKAR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW606Mo01 | Monoclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IP. |
| PAW606Mo01 | Polyclonal Antibody to Cholecystokinin A Receptor (CCKAR) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW606Mo01 | CLIA Kit for Cholecystokinin A Receptor (CCKAR) | CLIA assay for Antigen Detection |
| ELW606Mo01 | ELISA Kit for Cholecystokinin A Receptor (CCKAR) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning and functional expression of the human gallbladder cholecystokinin A receptor."
Biochem. Biophys. Res. Commun. 193:204-211(1993) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning, functional expression and chromosomal localization of the human cholecystokinin type A receptor."
Biochem. Biophys. Res. Commun. 194:811-818(1993) [PubMed] [Europe PMC] [Abstract]
"Abnormal processing of the human cholecystokinin receptor gene in association with gallstones and obesity."
Gastroenterology 109:1375-1380(1995) [PubMed] [Europe PMC] [Abstract]
"Gene structure of human cholecystokinin (CCK) type-A receptor: body fat content is related to CCK type-A receptor gene promoter polymorphism."
FEBS Lett. 466:264-266(2000) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Molecular complex of cholecystokinin-8 and N-terminus of the cholecystokinin A receptor by NMR spectroscopy."
Biochemistry 38:14775-14783(1999) [PubMed] [Europe PMC] [Abstract]
"Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin A receptor."
Biochemistry 40:3804-3809(2001) [PubMed] [Europe PMC] [Abstract]