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Nerve Growth Factor (NGF)

NGFB; Beta-NGF; HSAN5; NGF-B; Beta-Nerve Growth Factor

Nerve growth factor (NGF) is a naturally occurring molecule in the body which stimulates the growth and differentiation of the sympathetic and certain sensory nerves. NGF is a protein that consists of 3 types of polypeptide chains -- alpha, beta and gamma -- that interact to form the protein. The NGF beta chain (NGFB) is solely responsible for the nerve growth stimulating activity of NGF. The NGFB gene is in chromosome band 1p22. An ointment containing NGF has been reported to help heal bedsores (decubiti).This complex contains 2 identical 118-amino acid beta-chains, which are solely responsible for nerve growth stimulating activity of NGF. Human DNA fragments coding for NGF were identified by Zabel et al. (1984) using a mouse submaxillary cDNA probe.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W605Hu01 Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies MW605Hu22 Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
PW605Hu01 Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
LW605Hu71 Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits KEW605Hu ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
KCW605Hu CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W605Mu01 Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
PW605Mu01 Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits KEW605Mu ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W605Ra01 Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies MW605Ra21 Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
PW605Ra01 Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits KEW605Ra ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
KCW605Ra CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W605Po01 Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies MW605Po21 Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
PW605Po01 Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits KEW605Po ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W605Bo01 Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies MW605Bo21 Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
PW605Bo01 Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits KEW605Bo ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W605Si01 Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies MW605Si21 Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
PW605Si01 Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits KEW605Si ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W605Ga01 Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies MW605Ga21 Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
PW605Ga01 Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits KEW605Ga ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W605Gu01 Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies MW605Gu21 Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
PW605Gu01 Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits KEW605Gu ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Nerve Growth Factor (NGF) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Nerve Growth Factor (NGF) Bioactivity
Antibodies NONE Monoclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Nerve Growth Factor (NGF) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Nerve Growth Factor (NGF) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Nerve Growth Factor (NGF) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Nerve Growth Factor (NGF) CLIA assay for Antigen Detection

Reference

"Human beta-nerve growth factor gene sequence highly homologous to that of mouse."
Nature 303:821-825(1983) [PubMed] [Europe PMC] [Abstract]

"Sequence homology of human and mouse beta-NGF subunit genes."
Cold Spring Harb. Symp. Quant. Biol. 48:435-442(1983) [PubMed] [Europe PMC] [Abstract]

"cDNA sequence of human beta-NGF."
Nucleic Acids Res. 18:4020-4020(1990) [PubMed] [Europe PMC] [Abstract]

"Cloning and sequencing of the gene for premature beta nerve growth factor."
Zhongguo Ying Yong Sheng Li Xue Za Zhi 13:316-318(1997) [PubMed] [Europe PMC] [Abstract]

"Human-specific amino acid changes found in 103 protein-coding genes."
Mol. Biol. Evol. 21:936-944(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary."
Neuron 6:845-858(1991) [PubMed] [Europe PMC] [Abstract]

"The trk proto-oncogene encodes a receptor for nerve growth factor."
Cell 65:189-197(1991) [PubMed] [Europe PMC] [Abstract]

"Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI."
J. Biol. Chem. 285:11793-11799(2010) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor."
Nature 401:184-188(1999) [PubMed] [Europe PMC] [Abstract]

"Characterization of single-nucleotide polymorphisms in coding regions of human genes."
Nat. Genet. 22:231-238(1999) [PubMed] [Europe PMC] [Abstract]

Erratum
Nat. Genet. 23:373-373(1999)

"A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception."
Hum. Mol. Genet. 13:799-805(2004) [PubMed] [Europe PMC] [Abstract]

"A novel NGF mutation clarifies the molecular mechanism and extends the phenotypic spectrum of the HSAN5 neuropathy."
J. Med. Genet. 48:131-135(2011) [PubMed] [Europe PMC] [Abstract]

"Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort."
J. Neurol. 259:1673-1685(2012) [PubMed] [Europe PMC] [Abstract]