Creatine Kinase, Muscle (CKM)

CK-MM; CKMM; CK3; CK-M; MM-CK; M-CK; Creatine kinase M-type, N-terminally processed

SPN	W601
HGNC	1994
MGI	88413
PubMed	2796990
RGD	2358
UniProt	P06732
Wiki	CKM

CKM is a cytoplasmic enzyme involved in cellular energy homeostasis. The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine and between phospho-creatine and ADP. Its functional entity is a MM-CK homodimer in striated (sarcomeric) skeletal and cardiac muscle.In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Since no other organ than cardiac muscle expresses significant levels of MB-CK, this clinical test is still fairly reliable, together with troponin-T, for diagnosing a myocardial infarction.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W601Hu01	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	MW601Hu22	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	PW601Hu01	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	LW601Hu71	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	KEW601Hu	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W601Mu01	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	MW601Mu21	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	PW601Mu01	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	LW601Mu71	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	LW601Mu81	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	KEW601Mu	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W601Ra01	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NPW601Ra01	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	MW601Ra21	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	PW601Ra01	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	LW601Ra71	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	KEW601Ra	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W601Ca01	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	PW601Ca01	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W601Po01	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	PW601Po01	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	LW601Po71	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	LW601Po81	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W601Bo01	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	PW601Bo01	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W601Ga01	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	PW601Ga01	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W601Rb01	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	MW601Rb21	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	PW601Rb51	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	KEW601Rb	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Creatine Kinase, Muscle (CKM)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Creatine Kinase, Muscle (CKM)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Creatine Kinase, Muscle (CKM)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Creatine Kinase, Muscle (CKM)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Creatine Kinase, Muscle (CKM)	CLIA assay for Antigen Detection

Reference

"Isolation and sequence analysis of a full-length cDNA for human M creatine kinase."
Biochem. Biophys. Res. Commun. 140:981-989(1986) [PubMed] [Europe PMC] [Abstract]

"Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene."
J. Biol. Chem. 263:17142-17149(1988) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Muscle creatine kinase isoenzyme expression in adult human brain."
J. Biol. Chem. 265:6403-6409(1990) [PubMed] [Europe PMC] [Abstract]

"cDNA cloning and mapping of the human creatine kinase M gene to 19q13."
Am. J. Hum. Genet. 40:115-125(1987) [PubMed] [Europe PMC] [Abstract]

"Crystallization and preliminary X-ray analysis of human muscle creatine kinase."
Acta Crystallogr. D 55:669-670(1999) [PubMed] [Europe PMC] [Abstract]