Tumor Necrosis Factor Alpha (TNFa)
DIF; TNF-A; TNFSF2; Cachectin; Tumor Necrosis Factor Ligand Superfamily Member 2
TNFa is synthesized as a 26 kDa, type II transmembrane protein that is 233 amino acids in length. It contains a 30 amino acid (aa) cytoplasmic domain, a 26 aa transmembrane segment, and a 177 aa extracellular region. TNFa is assembled intracellularly to form a transmembrane, non-covalently-linked homotrimeric protein. The 157 aa residue soluble form of TNFa (sTNF-αis released from the C-terminus of the transmembrane protein through the activity of TNFa-converting enzyme (TACE), a membrane -bound disintegrin metalloproteinase. Rat cells known to express TNF-αinclude B cells, colonic columnar epithelial cells, NK and CD3 CD56 hepatic natural T cells, macrophages, monocytes and monocyte-derived dendritic cells, CD4 and CD8 T cells, mast cells, neutrophils, keratinocytes, plasma cells, and adipocytes.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Hu01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Hu22 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Hu01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
LW583Hu71 | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Hu | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
KCW583Hu | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Mu01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Mu21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Mu01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
LW583Mu71 | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Mu | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
KCW583Mu | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Ra01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Ra21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Ra01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
LW583Ra71 | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
LW583Ra81 | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Ra | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
KCW583Ra | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Ca01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Ca21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Ca01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
LW583Ca71 | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Ca | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Po01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Po21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Po01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
LW583Po81 | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Po | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Bo01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Bo21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Bo01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Bo | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
KCW583Bo | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Si01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Si21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Si01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
LW583Si81 | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Si | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Ga01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Ga01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Ga | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Ov01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Ov21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Ov01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
LW583Ov71 | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Rb01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Rb21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Rb51 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
LW583Rb71 | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Rb | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Gu01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Gu21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Gu01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Gu | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Eq01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Eq21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Eq01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Eq | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | W583Cp01 | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | MW583Cp21 | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
PW583Cp01 | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | KEW583Cp | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Tumor Necrosis Factor Alpha (TNFa) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Tumor Necrosis Factor Alpha (TNFa) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Tumor Necrosis Factor Alpha (TNFa) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Tumor Necrosis Factor Alpha (TNFa) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Tumor Necrosis Factor Alpha (TNFa) | CLIA assay for Antigen Detection |
Reference
"Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome."
Cold Spring Harb. Symp. Quant. Biol. 51:611-624(1986) [PubMed] [Europe PMC] [Abstract]
"Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin."
Nature 312:724-729(1984) [PubMed] [Europe PMC] [Abstract]
"Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor."
Nature 313:803-806(1985) [PubMed] [Europe PMC] [Abstract]
"Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization."
Nucleic Acids Res. 13:6361-6373(1985) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning of the complementary DNA for human tumor necrosis factor."
Science 228:149-154(1985) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor."
Eur. J. Biochem. 152:515-522(1985) [PubMed] [Europe PMC] [Abstract]
"Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment."
Nat. Genet. 3:137-145(1993) [PubMed] [Europe PMC] [Abstract]
"A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC."
J. Immunol. 162:4745-4754(1999) [PubMed] [Europe PMC] [Abstract]
"Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse."
Genome Res. 13:2621-2636(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"O-glycosylated species of natural human tumor-necrosis factor-alpha."
Eur. J. Biochem. 235:431-437(1996) [PubMed] [Europe PMC] [Abstract]
"Phosphorylation of the 26 kDa TNF precursor in monocytic cells and in transfected HeLa cells."
J. Inflamm. 45:152-160(1995) [PubMed] [Europe PMC] [Abstract]
"A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'."
EMBO J. 18:2119-2126(1999) [PubMed] [Europe PMC] [Abstract]
"Localization of the active site of human tumour necrosis factor (hTNF) by mutational analysis."
EMBO J. 10:827-836(1991) [PubMed] [Europe PMC] [Abstract]
"Myristyl acylation of the tumor necrosis factor alpha precursor on specific lysine residues."
J. Exp. Med. 176:1053-1062(1992) [PubMed] [Europe PMC] [Abstract]
"Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha."
Nature 385:733-736(1997) [PubMed] [Europe PMC] [Abstract]
"A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria."
Nat. Genet. 22:145-150(1999) [PubMed] [Europe PMC] [Abstract]
"SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production."
Nat. Cell Biol. 8:843-848(2006) [PubMed] [Europe PMC] [Abstract]
"A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b."
Nat. Cell Biol. 8:894-896(2006) [PubMed] [Europe PMC] [Abstract]
"Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-alpha in rheumatoid arthritis."
Nat. Med. 19:322-328(2013) [PubMed] [Europe PMC] [Abstract]
"Structure of tumour necrosis factor."
Nature 338:225-228(1989) [PubMed] [Europe PMC] [Abstract]
"The structure of tumour necrosis factor -- implications for biological function."
J. Cell Sci. Suppl. 13:11-18(1990) [PubMed] [Europe PMC] [Abstract]
"The structure of tumor necrosis factor-alpha at 2.6-A resolution. Implications for receptor binding."
J. Biol. Chem. 264:17595-17605(1989) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2."
Protein Eng. 10:1101-1107(1997) [PubMed] [Europe PMC] [Abstract]
"High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity."
J. Biol. Chem. 273:2153-2160(1998) [PubMed] [Europe PMC] [Abstract]
"Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity."
Arthritis Rheum. 48:1408-1413(2003) [PubMed] [Europe PMC] [Abstract]
"Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection."
Hum. Mol. Genet. 12:2541-2546(2003) [PubMed] [Europe PMC] [Abstract]