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Calnexin (CNX)

CANX; CNX; IP90; P90; Major Histocompatibility Complex Class I Antigen-Binding Protein p88

SPN W482
HGNC 1473
MGI 88261
PubMed 11583625
RGD 2266
UniProt P27824
Wiki Calnexin

Calnexin is a 90kDa integral protein of the endoplasmic reticulum. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short, acidic cytoplasmic tail. Calnexin is one of the chaperone molecules, which are characterized by their main function of assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Oligosaccharides with three sequential glucose residues are added to asparagine residues of the nascent proteins in the ER. The monoglucosylated oligosaccharides that are recognized by calnexin result from the trimming of two glucose residues by the sequential action of two glucosidases, I and II.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W482Hu01 Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies MW482Hu22 Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
PW482Hu01 Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits KEW482Hu ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
PW482Mu01 Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Calnexin (CNX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Calnexin (CNX) Bioactivity
Antibodies NONE Monoclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Calnexin (CNX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Calnexin (CNX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Calnexin (CNX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Calnexin (CNX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Calnexin (CNX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Calnexin (CNX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Calnexin (CNX) CLIA assay for Antigen Detection

Reference

"Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin)."
J. Biol. Chem. 268:9585-9592(1993) [PubMed] [Europe PMC] [Abstract]

"Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5."
Biochemistry 33:3229-3236(1994) [PubMed] [Europe PMC] [Abstract]

"The molecular chaperones HSP28, GRP78, endoplasmin, and calnexin exhibit strikingly different levels in quiescent keratinocytes as compared to their proliferating normal and transformed counterparts: cDNA cloning and expression of calnexin."
Electrophoresis 15:482-490(1994) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 5."
Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

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