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Lactoperoxidase (LPO)

SPO; Salivary peroxidase

Lactoperoxidase is a peroxidase enzyme found in milk. It is able to form reactive bromine and iodine species, resulting in natural organobromine and organoiodine substances, and can therefore be categorised as a haloperoxidase. It is fairly heat resistant and was widely used as an indicator of overpasteurization of milk.Freshly isolated and purified samples of goat LPO were saturated with ammonium iodide and crystallized using 20% polyethylene glycol 3350 in a hanging drop vapor diffusion setup. Goat LPO consists of a single polypeptide chain of 595 amino acid residues and folds into an oval-shaped structure. The structure contains 20 well-defined alpha-helices of varying lengths including a helix, H(2a), unique to LPO, and two short antiparallel beta-strands.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW467Hu01 Recombinant Lactoperoxidase (LPO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW467Hu01 Monoclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IP.
PAW467Hu01 Polyclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IF.
Assay Kits CLW467Hu01 CLIA Kit for Lactoperoxidase (LPO) CLIA assay for Antigen Detection
ELW467Hu01 ELISA Kit for Lactoperoxidase (LPO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW467Mu01 Recombinant Lactoperoxidase (LPO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW467Mu01 Monoclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IP.
PAW467Mu01 Polyclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IF.
Assay Kits CLW467Mu01 CLIA Kit for Lactoperoxidase (LPO) CLIA assay for Antigen Detection
ELW467Mu01 ELISA Kit for Lactoperoxidase (LPO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW467Ra01 Recombinant Lactoperoxidase (LPO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW467Ra01 Monoclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IP.
PAW467Ra01 Polyclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IF.
Assay Kits CLW467Ra01 CLIA Kit for Lactoperoxidase (LPO) CLIA assay for Antigen Detection
ELW467Ra01 ELISA Kit for Lactoperoxidase (LPO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW467Ca01 Recombinant Lactoperoxidase (LPO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW467Ca01 Monoclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IP.
PAW467Ca01 Polyclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IF.
Assay Kits CLW467Ca01 CLIA Kit for Lactoperoxidase (LPO) CLIA assay for Antigen Detection
ELW467Ca01 ELISA Kit for Lactoperoxidase (LPO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW467Po01 Recombinant Lactoperoxidase (LPO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW467Po01 Monoclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IP.
PAW467Po01 Polyclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IF.
Assay Kits CLW467Po01 CLIA Kit for Lactoperoxidase (LPO) CLIA assay for Antigen Detection
ELW467Po01 ELISA Kit for Lactoperoxidase (LPO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW467Bo01 Recombinant Lactoperoxidase (LPO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW467Bo01 Monoclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IP.
PAW467Bo01 Polyclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IF.
Assay Kits CLW467Bo01 CLIA Kit for Lactoperoxidase (LPO) CLIA assay for Antigen Detection
ELW467Bo01 ELISA Kit for Lactoperoxidase (LPO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW467Rb01 Recombinant Lactoperoxidase (LPO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW467Rb01 Monoclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IP.
PAW467Rb01 Polyclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IF.
Assay Kits CLW467Rb01 CLIA Kit for Lactoperoxidase (LPO) CLIA assay for Antigen Detection
ELW467Rb01 ELISA Kit for Lactoperoxidase (LPO) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW467Mo01 Recombinant Lactoperoxidase (LPO) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW467Mo01 Monoclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IP.
PAW467Mo01 Polyclonal Antibody to Lactoperoxidase (LPO) WB; IHC; ICC; IF.
Assay Kits CLW467Mo01 CLIA Kit for Lactoperoxidase (LPO) CLIA assay for Antigen Detection
ELW467Mo01 ELISA Kit for Lactoperoxidase (LPO) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Cloning and sequence analysis of the human salivary peroxidase-encoding cDNA."
Gene 173:261-264(1996) [PubMed] [Europe PMC] [Abstract]

"Molecular heterogeneity and alternative splicing of human lactoperoxidase."
Arch. Biochem. Biophys. 482:52-57(2009) [PubMed] [Europe PMC] [Abstract]

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning of cDNAs encoding bovine and human lactoperoxidase."
DNA Cell Biol. 9:499-509(1990) [PubMed] [Europe PMC] [Abstract]

"Lactoperoxidase and human airway host defense."
Am. J. Respir. Cell Mol. Biol. 29:206-212(2003) [PubMed] [Europe PMC] [Abstract]

"Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
J. Proteome Res. 5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]

"Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry."
Proteomics 8:3833-3847(2008) [PubMed] [Europe PMC] [Abstract]