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Matrix Metalloproteinase 15 (MMP15)

SMCP-2; MTMMP2; MT2-MMP; Membrane-Inserted; Membrane-type matrix metalloproteinase 2; Membrane-type-2 matrix metalloproteinase

The MMP15 cDNA encodes a 669-amino acid protein that has the typical structural features of an MMP. In addition, it contains a predicted transmembrane segment at the C terminus. MMP15 shares 73.9% sequence similarity with MMP14, a membrane-localized MMP that also contains a C-terminal transmembrane segment. the membrane-type MMPs are a subclass in the MMP family since the other members lack a C-terminal transmembrane domain and are secreted as soluble forms. Will and Hinzmann showed by immunoblotting that MMP15-specific antibodies detect a 72-kD protein in lung cell surface membranes, suggesting that MMP15 is membrane-bound. They demonstrated by Northern blotting that MMP15 is widely expressed as a 3.6-kb transcript, with highest levels in liver, placenta, testis, colon, and intestine.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W457Hu01 Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies MW457Hu22 Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
PW457Hu01 Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits KEW457Hu ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W457Mu01 Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
PW457Mu01 Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits KEW457Mu ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W457Po01 Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
PW457Po01 Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Matrix Metalloproteinase 15 (MMP15) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Matrix Metalloproteinase 15 (MMP15) Bioactivity
Antibodies NONE Monoclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Matrix Metalloproteinase 15 (MMP15) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Matrix Metalloproteinase 15 (MMP15) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Matrix Metalloproteinase 15 (MMP15) CLIA assay for Antigen Detection

Reference

"cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment."
Eur. J. Biochem. 231:602-608(1995) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization."
Genomics 39:412-413(1997) [PubMed] [Europe PMC] [Abstract]

"Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases."
Eur. J. Biochem. 250:751-757(1997) [PubMed] [Europe PMC] [Abstract]

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]