GATA Binding Protein 2 (GATA2)

NFE1B; Endothelial transcription factor GATA-2

SPN	W449
HGNC	4171
MGI	95662
PubMed	21892162
RGD	2664
UniProt	P23769
Wiki	GATA2

The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. GATA1 is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes.

GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells. In chicken erythroid progenitors, forced expression of GATA2 promotes proliferation at the expense of differentiation. GATA3 expression is restricted to T-lymphoid cells and some nonhematopoietic cell types, including embryonic stem cells.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W449Hu01	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	PW449Hu01	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	W449Mu01	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	PW449Mu01	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant GATA Binding Protein 2 (GATA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native GATA Binding Protein 2 (GATA2)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to GATA Binding Protein 2 (GATA2)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for GATA Binding Protein 2 (GATA2)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for GATA Binding Protein 2 (GATA2)	CLIA assay for Antigen Detection

Reference

"Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells."
J. Biol. Chem. 266:16188-16192(1991) [PubMed] [Europe PMC] [Abstract]

"Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells."
J. Biol. Chem. 267:1279-1285(1992) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome."
Blood 118:2653-2655(2011) [PubMed] [Europe PMC] [Abstract]

"Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)."
Nat. Genet. 43:929-931(2011) [PubMed] [Europe PMC] [Abstract]

"Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia."
Nat. Genet. 43:1012-1017(2011) [PubMed] [Europe PMC] [Abstract]