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Interleukin 27 (IL27)
Interleukin 27 (IL27)
p28; IL30; Interleukin 30; Interleukin-27 subunit alpha
Interleukin 27 is a non-covalently linked heterodimeric cytokine that is structurally related to IL-12. It is composed of an Epstein-Barr virus-induced molecule 3 subunit linked with the IL-27 p28 subunit. IL-27 is produced by activated antigen presenting cells including monocytes, endothelial cells, and dendritic cells.
Interleukin-30 (IL-30) is a protein with a molecular weight of 28 kilodaltons, which forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus is sometimes called IL27-p28. The other chain of IL-27 is a molecule called Epstein-Barr induced gene-3 (EBI3). IL-30 is a member of the long-chain, 4-helix bundle family of cytokines, making it structurally similar to IL-6. This gene for this molecule is now officially called IL-27 under HGNC guidelines.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W418Hu01
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
MW418Hu22
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
PW418Hu01
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
KEW418Hu
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
PW418Mu01
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
W418Ra01
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
MW418Ra21
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
PW418Ra01
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
KEW418Ra
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 27 (IL27) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 27 (IL27) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 27 (IL27) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 27 (IL27) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 27 (IL27) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 27 (IL27) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 27 (IL27) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 27 (IL27) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 27 (IL27) CLIA assay for Antigen Detection
Reference
"IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells." Immunity 16:779-790(2002) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells." J. Interferon Cytokine Res. 23:513-522(2003) [PubMed ] [Europe PMC ] [Abstract ]
"Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27." Blood 109:1841-1849(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Interleukin-27 upregulates major histocompatibility complex class II expression in primary human endothelial cells through induction of major histocompatibility complex class II transactivator." Hum. Immunol. 68:965-972(2007) [PubMed ] [Europe PMC ] [Abstract ]
"The biology and therapeutic potential of interleukin 27." J. Mol. Med. 85:661-672(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Identification of polymorphisms in human interleukin-27 and their association with asthma in a Korean population." J. Hum. Genet. 52:355-361(2007) [PubMed ] [Europe PMC ] [Abstract ]
