Inhibin A (INHA)
INH-A
Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits. Inhibin belongs to the transforming growth factor-β superfamily.In women, FSH stimulates the secretion of inhibin from the granulosa cells of the ovarian follicles in ovary. In turn, inhibin suppresses FSH.Inhibin secretion is diminished by GnRH, and enhanced by insulin-like growth factor-1.Inhibin A reaches its peak in the mid-luteal phase.
Inhibin-A is elevated in the blood serum of women carrying fetuses with Down syndrome.Inhibin is produced in the gonads, ituitary gland, placenta and other organs.In men, it is a hormone that inhibits FSH production.The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW408Hu01 | Recombinant Inhibin A (INHA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW408Hu01 | Monoclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IP. |
| PAW408Hu01 | Polyclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW408Hu01 | CLIA Kit for Inhibin A (INHA) | CLIA assay for Antigen Detection |
| ELW408Hu01 | ELISA Kit for Inhibin A (INHA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW408Mu01 | Recombinant Inhibin A (INHA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW408Mu01 | Monoclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IP. |
| PAW408Mu01 | Polyclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW408Mu01 | CLIA Kit for Inhibin A (INHA) | CLIA assay for Antigen Detection |
| ELW408Mu01 | ELISA Kit for Inhibin A (INHA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW408Ra01 | Recombinant Inhibin A (INHA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW408Ra01 | Monoclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IP. |
| PAW408Ra01 | Polyclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW408Ra01 | CLIA Kit for Inhibin A (INHA) | CLIA assay for Antigen Detection |
| ELW408Ra01 | ELISA Kit for Inhibin A (INHA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW408Ca01 | Recombinant Inhibin A (INHA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW408Ca01 | Monoclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IP. |
| PAW408Ca01 | Polyclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW408Ca01 | CLIA Kit for Inhibin A (INHA) | CLIA assay for Antigen Detection |
| ELW408Ca01 | ELISA Kit for Inhibin A (INHA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW408Po01 | Recombinant Inhibin A (INHA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW408Po01 | Monoclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IP. |
| PAW408Po01 | Polyclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW408Po01 | CLIA Kit for Inhibin A (INHA) | CLIA assay for Antigen Detection |
| ELW408Po01 | ELISA Kit for Inhibin A (INHA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW408Bo01 | Recombinant Inhibin A (INHA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW408Bo01 | Monoclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IP. |
| PAW408Bo01 | Polyclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW408Bo01 | CLIA Kit for Inhibin A (INHA) | CLIA assay for Antigen Detection |
| ELW408Bo01 | ELISA Kit for Inhibin A (INHA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW408Rb01 | Recombinant Inhibin A (INHA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW408Rb01 | Monoclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IP. |
| PAW408Rb01 | Polyclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW408Rb01 | CLIA Kit for Inhibin A (INHA) | CLIA assay for Antigen Detection |
| ELW408Rb01 | ELISA Kit for Inhibin A (INHA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW408Mo01 | Recombinant Inhibin A (INHA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW408Mo01 | Monoclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IP. |
| PAW408Mo01 | Polyclonal Antibody to Inhibin A (INHA) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW408Mo01 | CLIA Kit for Inhibin A (INHA) | CLIA assay for Antigen Detection |
| ELW408Mo01 | ELISA Kit for Inhibin A (INHA) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Inhibin A-subunit cDNAs from porcine ovary and human placenta."
Proc. Natl. Acad. Sci. U.S.A. 83:5849-5853(1986) [PubMed] [Europe PMC] [Abstract]
"Human inhibin genes. Genomic characterisation and sequencing."
FEBS Lett. 206:329-334(1986) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Structure of two human ovarian inhibins."
Biochem. Biophys. Res. Commun. 135:957-964(1986) [PubMed] [Europe PMC] [Abstract]
"Characterization and determination of the biological activities of noncleavable high molecular weight forms of inhibin A and activin A."
Mol. Endocrinol. 10:1055-1065(1996) [PubMed] [Europe PMC] [Abstract]
"Loss of the expression and localization of inhibin alpha-subunit in high grade prostate cancer."
J. Clin. Endocrinol. Metab. 83:969-975(1998) [PubMed] [Europe PMC] [Abstract]
"Inhibin: a candidate gene for premature ovarian failure."
Hum. Reprod. 15:2644-2649(2000) [PubMed] [Europe PMC] [Abstract]
"Germline mutations of inhibins in early-onset ovarian epithelial tumors."
Hum. Mutat. 35:294-297(2014) [PubMed] [Europe PMC] [Abstract]