Call Now

Caspase 7 (CASP7)

CMH1; ICE-LAP3; MCH3; Caspase 7 Apoptosis-Related Cysteine Peptidase; Cysteine Aspartate Protease 7; Cysteinyl Aspartate Specific Proteinases 7

Caspase-7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis.

Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing by upstream caspases (caspase-8, -9)at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme in the form of a heterotetramer. The precursor of this caspase is cleaved by caspase 3, caspase 10, and caspase 9. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W357Hu01 Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies MW357Hu22 Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
PW357Hu01 Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
LW357Hu71 Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits KEW357Hu ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W357Mu01 Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
PW357Mu01 Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
LW357Mu71 Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
LW357Mu81 FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits KEW357Mu ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W357Ra01 Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies MW357Ra21 Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
PW357Ra01 Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits KEW357Ra ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Caspase 7 (CASP7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Caspase 7 (CASP7) Bioactivity
Antibodies NONE Monoclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Caspase 7 (CASP7) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Caspase 7 (CASP7) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Caspase 7 (CASP7) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Caspase 7 (CASP7) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Caspase 7 (CASP7) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Caspase 7 (CASP7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Caspase 7 (CASP7) CLIA assay for Antigen Detection

Reference

"Mch3, a novel human apoptotic cysteine protease highly related to CPP32."
Cancer Res. 55:6045-6052(1995) [PubMed] [Europe PMC] [Abstract]

"ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis."
J. Biol. Chem. 271:1621-1625(1996) [PubMed] [Europe PMC] [Abstract]

"Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32."
J. Biol. Chem. 271:1825-1828(1996) [PubMed] [Europe PMC] [Abstract]

"Identification and mapping of Casp7, a cysteine protease resembling CPP32 beta, interleukin-1 beta converting enzyme, and CED-3."
Genomics 40:86-93(1997) [PubMed] [Europe PMC] [Abstract]

"Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains."
Proc. Natl. Acad. Sci. U.S.A. 93:7464-7469(1996) [PubMed] [Europe PMC] [Abstract]

"Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase."
Mol. Cell 14:801-811(2004) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding."
Cell 107:399-407(2001) [PubMed] [Europe PMC] [Abstract]