Calcitonin (CT)
CALCA; CALC1; CGRP-I; CGRP1; KC; CCP; PDN-21; Katacalcin; Calcitonin-Related Polypeptide Alpha; Calcitonin carboxyl-terminal peptide
The most prominent clinical syndrome associated with a disordered hypersecretion of Calcitonin is medullary carcinoma of the thyroid (MTC). MTC is a tumor of the Calcitonin producing C-cells of the thyroid gland. Although MTC is rare, comprising 5 - 10% of all thyroid cancer, it is often fatal. It may occur sporadically or in a familial form that is transmitted as an autosomal dominant trait. MTC has great clinical importance because of its familial distribution. Further, it leant itself to be diagnosed early by serum Calcitonin and total cure for early sub-clinical disease is possible1. This is frequently associated with other clinical features and it has good potential for cure with surgery. Although a rare tumor, it can occur in a familial pattern1 as a Type II multiple endocrine neoplasia.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | W334Hu01 | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | MW334Hu22 | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| PW334Hu01 | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| LW334Hu71 | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | W334Mu01 | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| PW334Mu01 | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | W334Ra01 | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | MW334Ra21 | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| PW334Ra01 | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | W334Ca01 | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | MW334Ca21 | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| PW334Ca01 | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| PW334Ga01 | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| LW334Ga71 | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Calcitonin (CT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Calcitonin (CT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Calcitonin (CT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Calcitonin (CT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Calcitonin (CT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Calcitonin (CT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Calcitonin (CT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Calcitonin (CT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Calcitonin (CT) | CLIA assay for Antigen Detection |
Reference
"The complete sequence of human preprocalcitonin."
FEBS Lett. 167:93-97(1984) [PubMed] [Europe PMC] [Abstract]
"Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression."
Proc. Natl. Acad. Sci. U.S.A. 82:1994-1998(1985) [PubMed] [Europe PMC] [Abstract]
"Expression and function of the human calcitonin/alpha-CGRP gene in health and disease."
Biochem. Soc. Symp. 52:91-105(1986) [PubMed] [Europe PMC] [Abstract]
"Ectopic synthesis of high-Mr calcitonin by the BEN lung carcinoma cell line reflects aberrant proteolytic processing."
FEBS Lett. 198:71-79(1986) [PubMed] [Europe PMC] [Abstract]
"A novel calcitonin carboxyl-terminal peptide produced in medullary thyroid carcinoma by alternative RNA processing of the calcitonin/calcitonin gene-related peptide gene."
J. Biol. Chem. 266:24627-24631(1991) [PubMed] [Europe PMC] [Abstract]
"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Structure and expression of a gene encoding human calcitonin and calcitonin gene related peptide."
Biochem. Biophys. Res. Commun. 123:648-655(1984) [PubMed] [Europe PMC] [Abstract]
"Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma."
EMBO J. 4:715-724(1985) [PubMed] [Europe PMC] [Abstract]
"Human calcitonin. Structure of calcitonin M and D."
Helv. Chim. Acta 51:1900-1905(1968) [PubMed] [Europe PMC] [Abstract]
"A 1H NMR study of human calcitonin in solution."
Biochemistry 30:2364-2371(1991) [PubMed] [Europe PMC] [Abstract]
"Katacalcin: a new plasma calcium-lowering hormone."
Lancet 1:846-848(1983) [PubMed] [Europe PMC] [Abstract]
"An unappreciated role for RNA surveillance."
Genome Biol. 5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]