Keratin 1 (KRT1)
CK1; EHK1; K1; KRT1A; KRT1-A; Cytokeratin 1; Epidermolytic Hyperkeratosis; Keratin, type II cytoskeletal 1; 67 kDa cytokeratin; Type-II keratin Kb1
The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.Keratin 1 is specifically expressed in the spinous and granular layers of the epidermis with family member keratin 10. Mutations in this gene have been associated with the variants of bullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW315Hu01 | Recombinant Keratin 1 (KRT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW315Hu01 | Monoclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IP. |
| PAW315Hu01 | Polyclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW315Hu01 | CLIA Kit for Keratin 1 (KRT1) | CLIA assay for Antigen Detection |
| ELW315Hu01 | ELISA Kit for Keratin 1 (KRT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW315Mu01 | Recombinant Keratin 1 (KRT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW315Mu01 | Monoclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IP. |
| PAW315Mu01 | Polyclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW315Mu01 | CLIA Kit for Keratin 1 (KRT1) | CLIA assay for Antigen Detection |
| ELW315Mu01 | ELISA Kit for Keratin 1 (KRT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW315Ra01 | Recombinant Keratin 1 (KRT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW315Ra01 | Monoclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IP. |
| PAW315Ra01 | Polyclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW315Ra01 | CLIA Kit for Keratin 1 (KRT1) | CLIA assay for Antigen Detection |
| ELW315Ra01 | ELISA Kit for Keratin 1 (KRT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW315Ca01 | Recombinant Keratin 1 (KRT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW315Ca01 | Monoclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IP. |
| PAW315Ca01 | Polyclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW315Ca01 | CLIA Kit for Keratin 1 (KRT1) | CLIA assay for Antigen Detection |
| ELW315Ca01 | ELISA Kit for Keratin 1 (KRT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW315Po01 | Recombinant Keratin 1 (KRT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW315Po01 | Monoclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IP. |
| PAW315Po01 | Polyclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW315Po01 | CLIA Kit for Keratin 1 (KRT1) | CLIA assay for Antigen Detection |
| ELW315Po01 | ELISA Kit for Keratin 1 (KRT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW315Bo01 | Recombinant Keratin 1 (KRT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW315Bo01 | Monoclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IP. |
| PAW315Bo01 | Polyclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW315Bo01 | CLIA Kit for Keratin 1 (KRT1) | CLIA assay for Antigen Detection |
| ELW315Bo01 | ELISA Kit for Keratin 1 (KRT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW315Rb01 | Recombinant Keratin 1 (KRT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW315Rb01 | Monoclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IP. |
| PAW315Rb01 | Polyclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW315Rb01 | CLIA Kit for Keratin 1 (KRT1) | CLIA assay for Antigen Detection |
| ELW315Rb01 | ELISA Kit for Keratin 1 (KRT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW315Mo01 | Recombinant Keratin 1 (KRT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW315Mo01 | Monoclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IP. |
| PAW315Mo01 | Polyclonal Antibody to Keratin 1 (KRT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW315Mo01 | CLIA Kit for Keratin 1 (KRT1) | CLIA assay for Antigen Detection |
| ELW315Mo01 | ELISA Kit for Keratin 1 (KRT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Structure of a gene for the human epidermal 67-kDa keratin."
Proc. Natl. Acad. Sci. U.S.A. 82:1896-1900(1985) [PubMed] [Europe PMC] [Abstract]
"Genomic organization and amplification of the human epidermal type II keratin genes K1 and K5."
Biochem. Biophys. Res. Commun. 274:149-152(2000) [PubMed] [Europe PMC] [Abstract]
"Novel splice site mutation in keratin 1 underlies mild epidermolytic palmoplantar keratoderma in three kindreds."
J. Invest. Dermatol. 116:606-609(2001) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The finished DNA sequence of human chromosome 12."
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]