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Nestin (NES)

Nestin is a type VI intermediate filament (IF) protein.These intermediate filament proteins are expressed mostly in nerve cells where they are implicated in the radial growth of the axon. Seven genes encode for the heavy (NF-H), medium (NF-M) and light neurofilament (NF-L) proteins, nestin and alpha-internexin in nerve cells, synemin alpha and desmuslin/synemin beta (two alternative transcripts of the DMN gene) in muscle cells, and syncoilin (also in muscle cells). Members of this group mostly preferentially coassemble as heteropolymers in tissues. Steinert et al. has shown that nestin forms homodimers and homotetramers but does not form IF by itself in vitro. In mixtures, nestin preferentially co-assembles with purified vimentin or the type IV IF protein -internexin to form heterodimer coiled-coil molecules.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW307Hu01 Recombinant Nestin (NES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW307Hu01 Monoclonal Antibody to Nestin (NES) WB; IHC; ICC; IP.
PAW307Hu01 Polyclonal Antibody to Nestin (NES) WB; IHC; ICC; IF.
Assay Kits CLW307Hu01 CLIA Kit for Nestin (NES) CLIA assay for Antigen Detection
ELW307Hu01 ELISA Kit for Nestin (NES) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW307Mu01 Recombinant Nestin (NES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW307Mu01 Monoclonal Antibody to Nestin (NES) WB; IHC; ICC; IP.
PAW307Mu01 Polyclonal Antibody to Nestin (NES) WB; IHC; ICC; IF.
Assay Kits CLW307Mu01 CLIA Kit for Nestin (NES) CLIA assay for Antigen Detection
ELW307Mu01 ELISA Kit for Nestin (NES) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW307Ra01 Recombinant Nestin (NES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW307Ra01 Monoclonal Antibody to Nestin (NES) WB; IHC; ICC; IP.
PAW307Ra01 Polyclonal Antibody to Nestin (NES) WB; IHC; ICC; IF.
Assay Kits CLW307Ra01 CLIA Kit for Nestin (NES) CLIA assay for Antigen Detection
ELW307Ra01 ELISA Kit for Nestin (NES) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW307Ca01 Recombinant Nestin (NES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW307Ca01 Monoclonal Antibody to Nestin (NES) WB; IHC; ICC; IP.
PAW307Ca01 Polyclonal Antibody to Nestin (NES) WB; IHC; ICC; IF.
Assay Kits CLW307Ca01 CLIA Kit for Nestin (NES) CLIA assay for Antigen Detection
ELW307Ca01 ELISA Kit for Nestin (NES) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW307Po01 Recombinant Nestin (NES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW307Po01 Monoclonal Antibody to Nestin (NES) WB; IHC; ICC; IP.
PAW307Po01 Polyclonal Antibody to Nestin (NES) WB; IHC; ICC; IF.
Assay Kits CLW307Po01 CLIA Kit for Nestin (NES) CLIA assay for Antigen Detection
ELW307Po01 ELISA Kit for Nestin (NES) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW307Bo01 Recombinant Nestin (NES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW307Bo01 Monoclonal Antibody to Nestin (NES) WB; IHC; ICC; IP.
PAW307Bo01 Polyclonal Antibody to Nestin (NES) WB; IHC; ICC; IF.
Assay Kits CLW307Bo01 CLIA Kit for Nestin (NES) CLIA assay for Antigen Detection
ELW307Bo01 ELISA Kit for Nestin (NES) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW307Rb01 Recombinant Nestin (NES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW307Rb01 Monoclonal Antibody to Nestin (NES) WB; IHC; ICC; IP.
PAW307Rb01 Polyclonal Antibody to Nestin (NES) WB; IHC; ICC; IF.
Assay Kits CLW307Rb01 CLIA Kit for Nestin (NES) CLIA assay for Antigen Detection
ELW307Rb01 ELISA Kit for Nestin (NES) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW307Mo01 Recombinant Nestin (NES) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW307Mo01 Monoclonal Antibody to Nestin (NES) WB; IHC; ICC; IP.
PAW307Mo01 Polyclonal Antibody to Nestin (NES) WB; IHC; ICC; IF.
Assay Kits CLW307Mo01 CLIA Kit for Nestin (NES) CLIA assay for Antigen Detection
ELW307Mo01 ELISA Kit for Nestin (NES) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

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"Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma."
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Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

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"Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]