Protein Kinase D2 (PKD2)
PRKD2; PRK-D2; PRKD-2; PK-D2; HSPC187; nPKC-D2; Serine/threonine-protein kinase D2
Serine/threonine-protein kinase D2 is encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
The addition of phosphatidyl-L-serine caused synergistic stimulation. Phorbol ester-activated PRKD2 migrated more slowly than inactive PRKD2 by SDS-PAGE, suggesting hyperphosphorylation upon activation.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| PW298Hu01 | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | W298Mu01 | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| PW298Mu01 | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Protein Kinase D2 (PKD2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Protein Kinase D2 (PKD2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Protein Kinase D2 (PKD2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Protein Kinase D2 (PKD2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Protein Kinase D2 (PKD2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Protein Kinase D2 (PKD2) | CLIA assay for Antigen Detection |
Reference
"Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase d family of serine threonine kinases."
J. Biol. Chem. 276:3310-3318(2001) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
"Mechanism of activation of protein kinase D2(PKD2) by the CCK(B)/gastrin receptor."
J. Biol. Chem. 277:29431-29436(2002) [PubMed] [Europe PMC] [Abstract]
"Protein kinase D2 mediates activation of nuclear factor kappaB by Bcr-Abl in Bcr-Abl+ human myeloid leukemia cells."
Cancer Res. 64:8939-8944(2004) [PubMed] [Europe PMC] [Abstract]
"Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network."
Nat. Cell Biol. 6:106-112(2004) [PubMed] [Europe PMC] [Abstract]
"Protein kinase D2 contributes to either IL-2 promoter regulation or induction of cell death upon TCR stimulation depending on its activity in Jurkat cells."
Int. Immunol. 18:1737-1747(2006) [PubMed] [Europe PMC] [Abstract]
"Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB."
Am. J. Physiol. 292:C767-C777(2007) [PubMed] [Europe PMC] [Abstract]
"Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2."
EMBO J. 26:4619-4633(2007) [PubMed] [Europe PMC] [Abstract]
"Angiotensin II directly triggers endothelial exocytosis via protein kinase C-dependent protein kinase D2 activation."
J. Pharmacol. Sci. 105:168-176(2007) [PubMed] [Europe PMC] [Abstract]
"Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family."
Biochem. J. 411:333-342(2008) [PubMed] [Europe PMC] [Abstract]
"Protein kinase D2 regulates chromogranin A secretion in human BON neuroendocrine tumour cells."
Cell. Signal. 20:925-934(2008) [PubMed] [Europe PMC] [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"PKD2 interacts with Lck and regulates NFAT activity in T cells."
BMB Rep. 42:35-40(2009) [PubMed] [Europe PMC] [Abstract]
"Identification of protein kinase D2 as a pivotal regulator of endothelial cell proliferation, migration, and angiogenesis."
J. Biol. Chem. 284:799-806(2009) [PubMed] [Europe PMC] [Abstract]
"Large-scale proteomics analysis of the human kinome."
Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis."
Oncogene 33:1167-1180(2014) [PubMed] [Europe PMC] [Abstract]
"Solution structure of the PH domain of protein kinase C, D2 type from human."
Submitted (NOV-2005) to the PDB data bank
"Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self."
Nat. Immunol. 9:1236-1243(2008) [PubMed] [Europe PMC] [Abstract]
"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]