S100 Calcium Binding Protein A11 (S100A11)

S100-A11; S100C; MLN70; Protein S100-C; Calgizzarin; Metastatic lymph node gene 70 protein; Protein S100-A11, N-terminally processed

SPN	W242
HGNC	10488
MGI	3645720
PubMed	18618420
RGD	1303295
UniProt	P31949
Wiki	S100A11

 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100C may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.By in situ hybridization, Moog-Lutz et al. mapped the calgizzarin, or S100C, gene to 1q21. By analysis of clones from this region, Wicki et al. determined that S100A11 is part of the S100 gene cluster and is located near S100A10

Reference

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