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Laminin Alpha 1 (LAMa1)

LAM-A1; LAMA; Laminin A; S-laminin subunit alpha

Laminin is a basement membrane protein composed of 3 nonidentical chains, A (400 kD), B1 (230 kD), and B2 (220 kD), which are arranged in a cross-shaped structure. Mattei et al. (1989) used in situ hybridization to localize the human laminin A locus to chromosome 18p11.31.By study of mouse-Chinese hamster somatic cell hybrids, Kaye et al. assigned the gene for laminin A to mouse chromosome 17 and confirmed the assignment of the gene for laminin B2 to mouse chromosome 1. Haaparanta et al. reported the nucleotide sequence of LAMA cDNA. They found an open reading frame encoding 3,075 amino acids. Nissinen et al. reported that the complete human laminin A chain contains a 17-amino acid signal peptide and a 3,058-residue A chain proper. The chain has a distinct domain structure with numerous internal cysteine-rich repeats.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W236Hu01 Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
PW236Hu02 Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
LW236Hu71 Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W236Mu01 Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
PW236Mu02 Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
LW236Mu71 Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits KEW236Mu ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W236Ra01 Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
PW236Ra01 Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits KEW236Ra ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Laminin Alpha 1 (LAMa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Laminin Alpha 1 (LAMa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Laminin Alpha 1 (LAMa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Laminin Alpha 1 (LAMa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Laminin Alpha 1 (LAMa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Laminin Alpha 1 (LAMa1) CLIA assay for Antigen Detection

Reference

"Molecular cloning of the cDNA encoding human laminin A chain."
Matrix 11:151-160(1991) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 18."
Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]

"Primary structure of the human laminin A chain. Limited expression in human tissues."
Biochem. J. 276:369-379(1991) [PubMed] [Europe PMC] [Abstract]

"Human laminin: cloning and sequence analysis of cDNAs encoding A, B1 and B2 chains, and expression of the corresponding genes in human skin and cultured cells."
Lab. Invest. 60:772-782(1989) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"Mutations in LAMA1 cause cerebellar dysplasia and cysts with and without retinal dystrophy."
Am. J. Hum. Genet. 95:227-234(2014) [PubMed] [Europe PMC] [Abstract]

"A secreted tyrosine kinase acts in the extracellular environment."
Cell 158:1033-1044(2014) [PubMed] [Europe PMC] [Abstract]