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Motilin (MTL)

MLN; MAP; Promotilin; Motilin-associated peptide

  • Motilin is a 22 amino acid polypeptide hormone, secreted by endocrine M cells that are numerous in crypts of the small intestine, especially in the duodenum and jejunum. Based on amino acid sequence, motilin is unrelated to other hormones. Because of its ability to stimulate gastric activity, it was named "Motilin". Apart from in humans, motilin receptors are found in the gastrointestinal tracts of pigs, rats, cows and cats and in the central nervous system of rabbits.

  • Motilin was discovered by Brown when he introduced alkaline solution into duodenum of dogs, which caused strong gastric contractions. Motilin has 22 amino acids and molecular weight of 2698. In extract from human gut and plasma, there are two basic forms of motilin. The first molecular form is the polypeptide of 22 amino acids.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W235Hu01 Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies MW235Hu21 Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
PW235Hu01 Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
LW235Hu71 Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W235Ra01 Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies MW235Ra21 Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
PW235Ra01 Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
PW235Po08 Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W235Bo01 Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
PW235Bo01 Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
PW235Rb51 Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Motilin (MTL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Motilin (MTL) Bioactivity
Antibodies NONE Monoclonal Antibody to Motilin (MTL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Motilin (MTL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Motilin (MTL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Motilin (MTL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Motilin (MTL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Motilin (MTL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Motilin (MTL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Motilin (MTL) CLIA assay for Antigen Detection

Reference

"Sequence of an intestinal cDNA encoding human motilin precursor."
FEBS Lett. 223:74-76(1987) [PubMed] [Europe PMC] [Abstract]

"Exon-intron organization, expression, and chromosomal localization of the human motilin gene."
FEBS Lett. 249:248-252(1989) [PubMed] [Europe PMC] [Abstract]

"Structure and expression of the human motilin gene."
DNA 8:615-621(1989) [PubMed] [Europe PMC] [Abstract]

"Molecular heterogeneity of human motilin-like immunoreactivity explained by the processing of prepromotilin."
Gastroenterology 96:695-703(1989) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"NMR solution structure and dynamics of motilin in isotropic phospholipid bicellar solution."
J. Biomol. NMR 24:103-112(2002) [PubMed] [Europe PMC] [Abstract]