Cyclin D1 (CCND1)
CCN-D1; BCL1; PRAD1; U21B31; G1/S-Specific Cyclin-D1; Parathyroid Adenomatosis 1; B-Cell CLL/Lymphoma 1; G1/S-Specific Cyclin D1; PRAD1 oncogene
Cyclin D1 belongs to the family of cyclin proteins which function as the regulatory subunits of cyclin/cyclin dependent kinase (Cdk) holoenzymes that regulate entry into and progression through the cell cycle. Cyclin D1 expression is induced upon stimulation by growth factors (e.g.EGF, IGF-I/II), amino acids, hormones, and oncogenes such as Ras, Src, ErbB2, and SV40 T antigen. Cdk4 and Cdk6 can partner with Cyclin D1 in early to mid-G1 phase to phosphorylate and inactivate the cell-cycle inhibitory function of the retinoblastoma protein (pRB) in cooperation with Cyclin E/Cdk2. Cyclin D1 is also known to modulate local chromatin structure and transcription of genes involved in proliferation and differentiation through CDK-independent association with histone acetylases (e.g. CBP, P/CAF) and deacetylases.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW225Hu01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW225Hu01 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
PAW225Hu01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IF. | |
Assay Kits | CLW225Hu01 | CLIA Kit for Cyclin D1 (CCND1) | CLIA assay for Antigen Detection |
ELW225Hu01 | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW225Mu01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW225Mu01 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
PAW225Mu01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IF. | |
Assay Kits | CLW225Mu01 | CLIA Kit for Cyclin D1 (CCND1) | CLIA assay for Antigen Detection |
ELW225Mu01 | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW225Ra01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW225Ra01 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
PAW225Ra01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IF. | |
Assay Kits | CLW225Ra01 | CLIA Kit for Cyclin D1 (CCND1) | CLIA assay for Antigen Detection |
ELW225Ra01 | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW225Ca01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW225Ca01 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
PAW225Ca01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IF. | |
Assay Kits | CLW225Ca01 | CLIA Kit for Cyclin D1 (CCND1) | CLIA assay for Antigen Detection |
ELW225Ca01 | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW225Po01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW225Po01 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
PAW225Po01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IF. | |
Assay Kits | CLW225Po01 | CLIA Kit for Cyclin D1 (CCND1) | CLIA assay for Antigen Detection |
ELW225Po01 | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW225Bo01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW225Bo01 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
PAW225Bo01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IF. | |
Assay Kits | CLW225Bo01 | CLIA Kit for Cyclin D1 (CCND1) | CLIA assay for Antigen Detection |
ELW225Bo01 | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW225Rb01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW225Rb01 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
PAW225Rb01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IF. | |
Assay Kits | CLW225Rb01 | CLIA Kit for Cyclin D1 (CCND1) | CLIA assay for Antigen Detection |
ELW225Rb01 | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPW225Mo01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAW225Mo01 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
PAW225Mo01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IF. | |
Assay Kits | CLW225Mo01 | CLIA Kit for Cyclin D1 (CCND1) | CLIA assay for Antigen Detection |
ELW225Mo01 | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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