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Toll Like Receptor 2 (TLR2)

CD282; TIL4; Toll/interleukin-1 receptor-like protein 4

TLR-2 plays a role in the immune system. TLR-2 is a membrane protein, a receptor, which is expressed on the surface of certain cells and recognizes foreign substances and passes on appropriate signals to the cells of the immune system. TLR-2 is a membrane receptor found at the surface of immune system cells that recognises many bacterial, fungal, viral and endogenous substances. Phagocytosis of bound materials takes place in endosome/phagosome and a cellular activation, so that the elements of the innate immune system take over such as macrophages, PMN and dendritic cells tasks of the nonspecific immune defense, B1a and form MZB first anti-bodies and uses in the process the specific anti-body formation.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W149Hu01 Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies MW149Hu21 Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
PW149Hu01 Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
LW149Hu71 Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits KEW149Hu ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W149Mu01 Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
PW149Mu01 Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits KEW149Mu ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W149Ra01 Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies MW149Ra21 Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
PW149Ra01 Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits KEW149Ra ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Toll Like Receptor 2 (TLR2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Toll Like Receptor 2 (TLR2) Bioactivity
Antibodies NONE Monoclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Toll Like Receptor 2 (TLR2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Toll Like Receptor 2 (TLR2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Toll Like Receptor 2 (TLR2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Toll Like Receptor 2 (TLR2) CLIA assay for Antigen Detection

Reference

"Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans."
Blood 91:4020-4027(1998) [PubMed] [Europe PMC] [Abstract]

"A family of human receptors structurally related to Drosophila Toll."
Proc. Natl. Acad. Sci. U.S.A. 95:588-593(1998) [PubMed] [Europe PMC] [Abstract]

"Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling."
Nature 395:284-288(1998) [PubMed] [Europe PMC] [Abstract]

"Natural selection in the TLR-related genes in the course of primate evolution."
Immunogenetics 60:727-735(2008) [PubMed] [Europe PMC] [Abstract]

"The heterogeneous allelic repertoire of human Toll-Like receptor (TLR) genes."
PLoS ONE 4:E7803-E7803(2009) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Cloning and sequencing of extracellular domain and its N-terminal and C-terminal fragments of Toll-like receptor 2."
Di 4 Jun Yi Da Xue Xue Bao 23:1085-1089(2002)

"Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2."
Science 285:736-739(1999) [PubMed] [Europe PMC] [Abstract]

"A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling."
J. Immunol. 169:6668-6672(2002) [PubMed] [Europe PMC] [Abstract]

"Four N-linked glycosylation sites in human toll-like receptor 2 cooperate to direct efficient biosynthesis and secretion."
J. Biol. Chem. 279:34589-34594(2004) [PubMed] [Europe PMC] [Abstract]

"TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3."
EMBO J. 32:566-582(2013) [PubMed] [Europe PMC] [Abstract]

"Structural basis for signal transduction by the Toll/interleukin-1 receptor domains."
Nature 408:111-115(2000) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide."
Cell 130:1071-1082(2007) [PubMed] [Europe PMC] [Abstract]

"Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients."
FEMS Immunol. Med. Microbiol. 31:53-58(2001) [PubMed] [Europe PMC] [Abstract]

"A Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling."
J. Immunol. 170:3451-3454(2003) [PubMed] [Europe PMC] [Abstract]

"Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family."
Hum. Mutat. 32:643-652(2011) [PubMed] [Europe PMC] [Abstract]