Alcohol Dehydrogenase 1 (ADH1)
ADH1A; Alcohol Dehydrogenase 1A(Class I)Alpha Polypeptide; Alcohol dehydrogenase subunit alpha
Alcohol dehydrogenase 1A is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism.
Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. This gene is monomorphic and predominant in fetal and infant livers, whereas the genes encoding beta and gamma subunits are polymorphic and strongly expressed in adult livers.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW131Hu01 | Recombinant Alcohol Dehydrogenase 1 (ADH1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW131Hu01 | Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IP. |
| PAW131Hu01 | Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW131Hu01 | CLIA Kit for Alcohol Dehydrogenase 1 (ADH1) | CLIA assay for Antigen Detection |
| ELW131Hu01 | ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW131Mu01 | Recombinant Alcohol Dehydrogenase 1 (ADH1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW131Mu01 | Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IP. |
| PAW131Mu01 | Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW131Mu01 | CLIA Kit for Alcohol Dehydrogenase 1 (ADH1) | CLIA assay for Antigen Detection |
| ELW131Mu01 | ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW131Ra01 | Recombinant Alcohol Dehydrogenase 1 (ADH1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW131Ra01 | Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IP. |
| PAW131Ra01 | Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW131Ra01 | CLIA Kit for Alcohol Dehydrogenase 1 (ADH1) | CLIA assay for Antigen Detection |
| ELW131Ra01 | ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW131Ca01 | Recombinant Alcohol Dehydrogenase 1 (ADH1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW131Ca01 | Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IP. |
| PAW131Ca01 | Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW131Ca01 | CLIA Kit for Alcohol Dehydrogenase 1 (ADH1) | CLIA assay for Antigen Detection |
| ELW131Ca01 | ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW131Po01 | Recombinant Alcohol Dehydrogenase 1 (ADH1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW131Po01 | Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IP. |
| PAW131Po01 | Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW131Po01 | CLIA Kit for Alcohol Dehydrogenase 1 (ADH1) | CLIA assay for Antigen Detection |
| ELW131Po01 | ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW131Bo01 | Recombinant Alcohol Dehydrogenase 1 (ADH1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW131Bo01 | Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IP. |
| PAW131Bo01 | Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW131Bo01 | CLIA Kit for Alcohol Dehydrogenase 1 (ADH1) | CLIA assay for Antigen Detection |
| ELW131Bo01 | ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW131Rb01 | Recombinant Alcohol Dehydrogenase 1 (ADH1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW131Rb01 | Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IP. |
| PAW131Rb01 | Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW131Rb01 | CLIA Kit for Alcohol Dehydrogenase 1 (ADH1) | CLIA assay for Antigen Detection |
| ELW131Rb01 | ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW131Mo01 | Recombinant Alcohol Dehydrogenase 1 (ADH1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW131Mo01 | Monoclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IP. |
| PAW131Mo01 | Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW131Mo01 | CLIA Kit for Alcohol Dehydrogenase 1 (ADH1) | CLIA assay for Antigen Detection |
| ELW131Mo01 | ELISA Kit for Alcohol Dehydrogenase 1 (ADH1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"cDNA and protein structure for the alpha subunit of human liver alcohol dehydrogenase."
Biochemistry 25:2465-2470(1986) [PubMed] [Europe PMC] [Abstract]
"Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence."
Proc. Natl. Acad. Sci. U.S.A. 83:634-638(1986) [PubMed] [Europe PMC] [Abstract]
"Molecular structure of the human alcohol dehydrogenase 1 gene."
FEBS Lett. 243:57-60(1989) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome."
Genomics 7:152-158(1990) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors."
Biochemistry 43:12555-12562(2004) [PubMed] [Europe PMC] [Abstract]
"Three-dimensional structures of the three human class I alcohol dehydrogenases."
Protein Sci. 10:697-706(2001) [PubMed] [Europe PMC] [Abstract]