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Desmoglein 1 (DSG1)
Desmoglein 1 (DSG1)
CDHF4; DG1; DSG; Cadherin family member 4; Desmosomal glycoprotein 1; Pemphigus foliaceus antigen
Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, four desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.From restriction enzyme analysis, they showed that the order of the DSG genes and their orientation is as follows: 5-prime--DSG1--DSG3--DSG2--3-prime. The desmoglein isoforms are expressed in a stratification-related manner in human epidermis, DSG1 being suprabasally expressed and DSG3 at a lower level, while DSG2 expression is weak and basal.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Desmoglein 1 (DSG1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Desmoglein 1 (DSG1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Desmoglein 1 (DSG1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Desmoglein 1 (DSG1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Desmoglein 1 (DSG1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Desmoglein 1 (DSG1) CLIA assay for Antigen Detection
Reference
"Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules." Proc. Natl. Acad. Sci. U.S.A. 88:4796-4800(1991) [PubMed ] [Europe PMC ] [Abstract ]
"Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome." PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"DNA sequence and analysis of human chromosome 18." Nature 437:551-555(2005) [PubMed ] [Europe PMC ] [Abstract ]
"N-terminal deletion in a desmosomal cadherin causes the autosomal dominant skin disease striate palmoplantar keratoderma." Hum. Mol. Genet. 8:971-976(1999) [PubMed ] [Europe PMC ] [Abstract ]
"Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry." J. Proteome Res. 5:1493-1503(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes." J. Biol. Chem. 284:31776-31788(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Sci. Signal. 3:RA3-RA3(2010) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting." Nat. Genet. 45:1244-1248(2013) [PubMed ] [Europe PMC ] [Abstract ]
