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Trefoil Factor 2 (TFF2)

SML1; SP; Spasmolytic Protein 1; Spasmolysin; Spasmolytic polypeptide

SPN W064
HGNC 11756
MGI 1306805
PubMed 11805131
RGD 620709
UniProt Q03403
Wiki TFF2

Trefoil factor 2 is aMember of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

The porcine gene was used to clone human and mouse SP cDNAs from stomach cDNA libraries. The human SP cDNA encodes a predicted 129-amino acid protein.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW064Hu01 Recombinant Trefoil Factor 2 (TFF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW064Hu01 Monoclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IP.
PAW064Hu01 Polyclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IF.
Assay Kits CLW064Hu01 CLIA Kit for Trefoil Factor 2 (TFF2) CLIA assay for Antigen Detection
ELW064Hu01 ELISA Kit for Trefoil Factor 2 (TFF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW064Mu01 Recombinant Trefoil Factor 2 (TFF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW064Mu01 Monoclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IP.
PAW064Mu01 Polyclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IF.
Assay Kits CLW064Mu01 CLIA Kit for Trefoil Factor 2 (TFF2) CLIA assay for Antigen Detection
ELW064Mu01 ELISA Kit for Trefoil Factor 2 (TFF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW064Ra01 Recombinant Trefoil Factor 2 (TFF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW064Ra01 Monoclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IP.
PAW064Ra01 Polyclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IF.
Assay Kits CLW064Ra01 CLIA Kit for Trefoil Factor 2 (TFF2) CLIA assay for Antigen Detection
ELW064Ra01 ELISA Kit for Trefoil Factor 2 (TFF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW064Ca01 Recombinant Trefoil Factor 2 (TFF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW064Ca01 Monoclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IP.
PAW064Ca01 Polyclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IF.
Assay Kits CLW064Ca01 CLIA Kit for Trefoil Factor 2 (TFF2) CLIA assay for Antigen Detection
ELW064Ca01 ELISA Kit for Trefoil Factor 2 (TFF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW064Po01 Recombinant Trefoil Factor 2 (TFF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW064Po01 Monoclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IP.
PAW064Po01 Polyclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IF.
Assay Kits CLW064Po01 CLIA Kit for Trefoil Factor 2 (TFF2) CLIA assay for Antigen Detection
ELW064Po01 ELISA Kit for Trefoil Factor 2 (TFF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW064Bo01 Recombinant Trefoil Factor 2 (TFF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW064Bo01 Monoclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IP.
PAW064Bo01 Polyclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IF.
Assay Kits CLW064Bo01 CLIA Kit for Trefoil Factor 2 (TFF2) CLIA assay for Antigen Detection
ELW064Bo01 ELISA Kit for Trefoil Factor 2 (TFF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW064Rb01 Recombinant Trefoil Factor 2 (TFF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW064Rb01 Monoclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IP.
PAW064Rb01 Polyclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IF.
Assay Kits CLW064Rb01 CLIA Kit for Trefoil Factor 2 (TFF2) CLIA assay for Antigen Detection
ELW064Rb01 ELISA Kit for Trefoil Factor 2 (TFF2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPW064Mo01 Recombinant Trefoil Factor 2 (TFF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAW064Mo01 Monoclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IP.
PAW064Mo01 Polyclonal Antibody to Trefoil Factor 2 (TFF2) WB; IHC; ICC; IF.
Assay Kits CLW064Mo01 CLIA Kit for Trefoil Factor 2 (TFF2) CLIA assay for Antigen Detection
ELW064Mo01 ELISA Kit for Trefoil Factor 2 (TFF2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma."
EMBO J. 9:407-414(1990) [PubMed] [Europe PMC] [Abstract]

"The three human trefoil genes TFF1, TFF2, and TFF3 are located within a region of 55 kb on chromosome 21q22.3."
Genomics 40:200-202(1997) [PubMed] [Europe PMC] [Abstract]

"Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region."
Genomics 68:22-29(2000) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

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