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Podocalyxin (PCX)

Gp200; PCLP; PC; PODXL; Podocalyxin Like Protein 1; GCTM-2 antigen

Podocalyxin belongs to the CD34/Podocalyxin family of sialomucins that share structural similarity and sequence homology. Podocalyxin is a major sialoprotein in the podocytes of the kidney glomerulus and is also expressed by both endothelium and multipotent hematopoietic progenitors. It has been identified as a novel cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells.The  protein was originally identified as an important component of glomerular podocytes. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W044Hu01 Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies MW044Hu22 Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
PW044Hu01 Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits KEW044Hu ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W044Mu01 Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
PW044Mu01 Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits KEW044Mu ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W044Ra01 Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies MW044Ra21 Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
PW044Ra01 Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits KEW044Ra ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Podocalyxin (PCX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Podocalyxin (PCX) Bioactivity
Antibodies NONE Monoclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Podocalyxin (PCX) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Podocalyxin (PCX) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Podocalyxin (PCX) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Podocalyxin (PCX) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Podocalyxin (PCX) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Podocalyxin (PCX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Podocalyxin (PCX) CLIA assay for Antigen Detection

Reference

"Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 and rat podocalyxin."
J. Biol. Chem. 272:15708-15714(1997) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 7: DNA sequence and biology."
Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human embryonal carcinoma tumor antigen, Gp200/GCTM-2, is podocalyxin."
Biochem. Biophys. Res. Commun. 300:285-290(2003) [PubMed] [Europe PMC] [Abstract]

"Podocalyxin increases the aggressive phenotype of breast and prostate cancer cells in vitro through its interaction with ezrin."
Cancer Res. 67:6183-6191(2007) [PubMed] [Europe PMC] [Abstract]

"Expression of podocalyxin enhances the adherence, migration, and intercellular communication of cells."
Exp. Cell Res. 314:2004-2015(2008) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]