Caspase 5 (CASP5)
ICE(rel)III; Cysteinyl Aspartate Specific Proteinases 5; Apoptosis-Related Cysteine Peptidase; Protease ICH-3; Protease TY
Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW042Hu01 | Recombinant Caspase 5 (CASP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW042Hu01 | Monoclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IP. |
| PAW042Hu01 | Polyclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW042Hu01 | CLIA Kit for Caspase 5 (CASP5) | CLIA assay for Antigen Detection |
| ELW042Hu01 | ELISA Kit for Caspase 5 (CASP5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW042Mu01 | Recombinant Caspase 5 (CASP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW042Mu01 | Monoclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IP. |
| PAW042Mu01 | Polyclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW042Mu01 | CLIA Kit for Caspase 5 (CASP5) | CLIA assay for Antigen Detection |
| ELW042Mu01 | ELISA Kit for Caspase 5 (CASP5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW042Ra01 | Recombinant Caspase 5 (CASP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW042Ra01 | Monoclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IP. |
| PAW042Ra01 | Polyclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW042Ra01 | CLIA Kit for Caspase 5 (CASP5) | CLIA assay for Antigen Detection |
| ELW042Ra01 | ELISA Kit for Caspase 5 (CASP5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW042Ca01 | Recombinant Caspase 5 (CASP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW042Ca01 | Monoclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IP. |
| PAW042Ca01 | Polyclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW042Ca01 | CLIA Kit for Caspase 5 (CASP5) | CLIA assay for Antigen Detection |
| ELW042Ca01 | ELISA Kit for Caspase 5 (CASP5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW042Po01 | Recombinant Caspase 5 (CASP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW042Po01 | Monoclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IP. |
| PAW042Po01 | Polyclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW042Po01 | CLIA Kit for Caspase 5 (CASP5) | CLIA assay for Antigen Detection |
| ELW042Po01 | ELISA Kit for Caspase 5 (CASP5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW042Bo01 | Recombinant Caspase 5 (CASP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW042Bo01 | Monoclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IP. |
| PAW042Bo01 | Polyclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW042Bo01 | CLIA Kit for Caspase 5 (CASP5) | CLIA assay for Antigen Detection |
| ELW042Bo01 | ELISA Kit for Caspase 5 (CASP5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW042Rb01 | Recombinant Caspase 5 (CASP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW042Rb01 | Monoclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IP. |
| PAW042Rb01 | Polyclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW042Rb01 | CLIA Kit for Caspase 5 (CASP5) | CLIA assay for Antigen Detection |
| ELW042Rb01 | ELISA Kit for Caspase 5 (CASP5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW042Mo01 | Recombinant Caspase 5 (CASP5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW042Mo01 | Monoclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IP. |
| PAW042Mo01 | Polyclonal Antibody to Caspase 5 (CASP5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW042Mo01 | CLIA Kit for Caspase 5 (CASP5) | CLIA assay for Antigen Detection |
| ELW042Mo01 | ELISA Kit for Caspase 5 (CASP5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
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