Hypoxia Inducible Factor 1 Alpha (HIF1a)
HIF1-A; MOP1; PASD8; Basic Helix-Loop-Helix Transcription Factor; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78
The HIF (hypoxia-inducible factor) transcription factor is a member of the basic-helix-loop-helix (bHLH) family of transcription factors and plays an important role in maintaining cellular oxygen homeostasis. The hypoxia-inducible transcription factor 1α (HIF-1α) is the regulated member of the transcription factor heterodimer HIF-1. HIF-1α has emerged as an important drug target in breast and prostate cancer, cardiovascular disease, and ischemia.
HIF-1alpha abundance (and its subsequent activity) is regulated transcriptionally in an NF-κB dependent manner. In addition, the coordinated activity of the prolyl hydroxylases (PHDs) maintain the appropriate balance of HIF-1α protein in the post-translation phase.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW014Hu01 | Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW014Hu01 | Monoclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IP. |
| PAW014Hu01 | Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW014Hu01 | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | CLIA assay for Antigen Detection |
| ELW014Hu01 | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW014Mu01 | Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW014Mu01 | Monoclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IP. |
| PAW014Mu01 | Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW014Mu01 | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | CLIA assay for Antigen Detection |
| ELW014Mu01 | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW014Ra01 | Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW014Ra01 | Monoclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IP. |
| PAW014Ra01 | Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW014Ra01 | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | CLIA assay for Antigen Detection |
| ELW014Ra01 | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW014Ca01 | Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW014Ca01 | Monoclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IP. |
| PAW014Ca01 | Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW014Ca01 | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | CLIA assay for Antigen Detection |
| ELW014Ca01 | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW014Po01 | Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW014Po01 | Monoclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IP. |
| PAW014Po01 | Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW014Po01 | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | CLIA assay for Antigen Detection |
| ELW014Po01 | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW014Bo01 | Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW014Bo01 | Monoclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IP. |
| PAW014Bo01 | Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW014Bo01 | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | CLIA assay for Antigen Detection |
| ELW014Bo01 | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW014Rb01 | Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW014Rb01 | Monoclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IP. |
| PAW014Rb01 | Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW014Rb01 | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | CLIA assay for Antigen Detection |
| ELW014Rb01 | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPW014Mo01 | Recombinant Hypoxia Inducible Factor 1 Alpha (HIF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAW014Mo01 | Monoclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IP. |
| PAW014Mo01 | Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a) | WB; IHC; ICC; IF. | |
| Assay Kits | CLW014Mo01 | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | CLIA assay for Antigen Detection |
| ELW014Mo01 | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Enzyme-linked immunosorbent assay for Antigen Detection |
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