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Pregnancy Associated Plasma Protein A (PAPPA)

PAPP-A; PAPA; ASBABP2; DIPLA1; IGFBP-4ase; PAPPA1; Pappalysin 1; Insulin-Like Growth Factor Binding Protein-4 Protease; Differentially Placenta 1 Expressed Protein

  • PAPP-A is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down’s syndrome. a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses (fetuses with an abnormal number of chromosomes). For example, low PAPPA may be seen in prenatal screening for Down syndrome.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W012Hu01 Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies MW012Hu22 Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
PW012Hu01 Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
LW012Hu71 Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits KEW012Hu ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins W012Mu01 Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
PW012Mu01 Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
LW012Mu71 Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
LW012Mu81 FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits KEW012Mu ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Pregnancy Associated Plasma Protein A (PAPPA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Pregnancy Associated Plasma Protein A (PAPPA) Bioactivity
Antibodies NONE Monoclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Pregnancy Associated Plasma Protein A (PAPPA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Pregnancy Associated Plasma Protein A (PAPPA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Pregnancy Associated Plasma Protein A (PAPPA) CLIA assay for Antigen Detection

Reference

"Complete cDNA sequence of the preproform of human pregnancy-associated plasma protein-A. Evidence for expression in the brain and induction by cAMP."
Eur. J. Biochem. 237:159-163(1996) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Amino acid sequence of human pregnancy-associated plasma protein-A derived from cloned cDNA."
Biochemistry 33:1592-1598(1994) [PubMed] [Europe PMC] [Abstract]

"Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein."
J. Biol. Chem. 268:12243-12246(1993) [PubMed] [Europe PMC] [Abstract]

"Complex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachment sites."
J. Biol. Chem. 278:2106-2117(2003) [PubMed] [Europe PMC] [Abstract]

"The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A."
Proc. Natl. Acad. Sci. U.S.A. 96:3149-3153(1999) [PubMed] [Europe PMC] [Abstract]

"Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor."
J. Biol. Chem. 275:31128-31133(2000) [PubMed] [Europe PMC] [Abstract]

"Localization of pregnancy-associated plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta."
Lab. Invest. 71:560-566(1994) [PubMed] [Europe PMC] [Abstract]

"Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissues."
Biol. Reprod. 61:1083-1089(1999) [PubMed] [Europe PMC] [Abstract]

"Identification of angiotensinogen and complement C3dg as novel proteins binding the proform of eosinophil major basic protein in human pregnancy serum and plasma."
J. Biol. Chem. 270:13645-13651(1995) [PubMed] [Europe PMC] [Abstract]

"Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A."
FEBS Lett. 504:36-40(2001) [PubMed] [Europe PMC] [Abstract]

"Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene."
Am. J. Hum. Genet. 70:663-672(2002) [PubMed] [Europe PMC] [Abstract]