Call Now

Prolactin (PRL)

LTH; Luteotropic Hormone

Luteotropic hormone is a peptide hormone discovered by Dr. Henry Friesen, primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of prolactin, which fills the breast with milk via a process called lactogenesis, in preparation for the next feed. Oxytocin, another hormone, is also released, which triggers milk let-down.Prolactin (PRL) is a peptide hormone primarily associated with lactation. In breastfeeding, the infant suckling the teat stimulates the production of prolactin, which fills the breast with milk (lactogenesis) in preparation for the next feed. Oxytocin, a similar hormone, is also released, which triggers milk let-down. Prolactin (PRL) is a polypeptide hormone secreted by anterior pituitary of both male and female.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV965Hu01 Recombinant Prolactin (PRL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV965Hu01 Monoclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IP.
PAV965Hu01 Polyclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IF.
Assay Kits CLV965Hu01 CLIA Kit for Prolactin (PRL) CLIA assay for Antigen Detection
ELV965Hu01 ELISA Kit for Prolactin (PRL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV965Mu01 Recombinant Prolactin (PRL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV965Mu01 Monoclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IP.
PAV965Mu01 Polyclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IF.
Assay Kits CLV965Mu01 CLIA Kit for Prolactin (PRL) CLIA assay for Antigen Detection
ELV965Mu01 ELISA Kit for Prolactin (PRL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV965Ra01 Recombinant Prolactin (PRL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV965Ra01 Monoclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IP.
PAV965Ra01 Polyclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IF.
Assay Kits CLV965Ra01 CLIA Kit for Prolactin (PRL) CLIA assay for Antigen Detection
ELV965Ra01 ELISA Kit for Prolactin (PRL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV965Ca01 Recombinant Prolactin (PRL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV965Ca01 Monoclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IP.
PAV965Ca01 Polyclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IF.
Assay Kits CLV965Ca01 CLIA Kit for Prolactin (PRL) CLIA assay for Antigen Detection
ELV965Ca01 ELISA Kit for Prolactin (PRL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV965Po01 Recombinant Prolactin (PRL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV965Po01 Monoclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IP.
PAV965Po01 Polyclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IF.
Assay Kits CLV965Po01 CLIA Kit for Prolactin (PRL) CLIA assay for Antigen Detection
ELV965Po01 ELISA Kit for Prolactin (PRL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV965Bo01 Recombinant Prolactin (PRL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV965Bo01 Monoclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IP.
PAV965Bo01 Polyclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IF.
Assay Kits CLV965Bo01 CLIA Kit for Prolactin (PRL) CLIA assay for Antigen Detection
ELV965Bo01 ELISA Kit for Prolactin (PRL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV965Rb01 Recombinant Prolactin (PRL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV965Rb01 Monoclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IP.
PAV965Rb01 Polyclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IF.
Assay Kits CLV965Rb01 CLIA Kit for Prolactin (PRL) CLIA assay for Antigen Detection
ELV965Rb01 ELISA Kit for Prolactin (PRL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV965Mo01 Recombinant Prolactin (PRL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV965Mo01 Monoclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IP.
PAV965Mo01 Polyclonal Antibody to Prolactin (PRL) WB; IHC; ICC; IF.
Assay Kits CLV965Mo01 CLIA Kit for Prolactin (PRL) CLIA assay for Antigen Detection
ELV965Mo01 ELISA Kit for Prolactin (PRL) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Human prolactin. cDNA structural analysis and evolutionary comparisons."
J. Biol. Chem. 256:4007-4016(1981) [PubMed] [Europe PMC] [Abstract]

"Isolation and characterization of the human prolactin gene."
EMBO J. 3:429-437(1984) [PubMed] [Europe PMC] [Abstract]

"A placenta-specific 5'non-coding exon of human prolactin."
Mol. Cell. Endocrinol. 75:71-80(1991) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning and nucleotide sequence of DNA complementary to human decidual prolactin mRNA."
J. Biochem. 95:1491-1499(1984) [PubMed] [Europe PMC] [Abstract]

"Expression of the prolactin gene in normal and neoplastic human breast tissues and human mammary cell lines: promoter usage and alternative mRNA splicing."
Breast Cancer Res. Treat. 44:243-253(1997) [PubMed] [Europe PMC] [Abstract]

"Human pituitary prolactin (hPRL): the entire linear amino acid sequence."
J. Clin. Endocrinol. Metab. 45:1112-1115(1977) [PubMed] [Europe PMC] [Abstract]

"High sensitivity automated sequence determination of polypeptides."
J. Biol. Chem. 250:3629-3636(1975) [PubMed] [Europe PMC] [Abstract]

"Immunoglobulin G subclasses and prolactin (PRL) isoforms in macroprolactinemia due to anti-PRL autoantibodies."
J. Clin. Endocrinol. Metab. 90:3036-3044(2005) [PubMed] [Europe PMC] [Abstract]

"The tertiary structure and backbone dynamics of human prolactin."
J. Mol. Biol. 328:1105-1121(2003) [PubMed] [Europe PMC] [Abstract]

"Solution structure of human prolactin."
J. Mol. Biol. 351:810-823(2005) [PubMed] [Europe PMC] [Abstract]

"Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL."
J. Biol. Chem. 282:33118-33131(2007) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor."
J. Biol. Chem. 283:19085-19094(2008) [PubMed] [Europe PMC] [Abstract]