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Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4)

CD252; TXGP1; OX40L; Gp34; OX40-L; Tax-Transcriptionally Activated Glycoprotein 1,34kD; Glycoprotein Gp34; OX40 ligand

OX40L(TNFSF4;CD252) is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells.

This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV961Hu01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV961Hu01 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IP.
PAV961Hu01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IF.
Assay Kits CLV961Hu01 CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) CLIA assay for Antigen Detection
ELV961Hu01 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV961Mu01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV961Mu01 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IP.
PAV961Mu01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IF.
Assay Kits CLV961Mu01 CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) CLIA assay for Antigen Detection
ELV961Mu01 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV961Ra01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV961Ra01 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IP.
PAV961Ra01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IF.
Assay Kits CLV961Ra01 CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) CLIA assay for Antigen Detection
ELV961Ra01 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV961Ca01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV961Ca01 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IP.
PAV961Ca01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IF.
Assay Kits CLV961Ca01 CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) CLIA assay for Antigen Detection
ELV961Ca01 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV961Po01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV961Po01 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IP.
PAV961Po01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IF.
Assay Kits CLV961Po01 CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) CLIA assay for Antigen Detection
ELV961Po01 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV961Bo01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV961Bo01 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IP.
PAV961Bo01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IF.
Assay Kits CLV961Bo01 CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) CLIA assay for Antigen Detection
ELV961Bo01 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV961Rb01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV961Rb01 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IP.
PAV961Rb01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IF.
Assay Kits CLV961Rb01 CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) CLIA assay for Antigen Detection
ELV961Rb01 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPV961Mo01 Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAV961Mo01 Monoclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IP.
PAV961Mo01 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) WB; IHC; ICC; IF.
Assay Kits CLV961Mo01 CLIA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) CLIA assay for Antigen Detection
ELV961Mo01 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax."
Mol. Cell. Biol. 11:1313-1325(1991) [PubMed] [Europe PMC] [Abstract]

"Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor."
J. Exp. Med. 180:757-762(1994) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"New variations in human OX40 ligand (CD134L) gene."
Genes Immun. 1:521-522(2000) [PubMed] [Europe PMC] [Abstract]

"Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34."
EMBO J. 13:3992-4001(1994) [PubMed] [Europe PMC] [Abstract]

"Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus."
Nat. Genet. 40:83-89(2008) [PubMed] [Europe PMC] [Abstract]

"The crystal structure of the costimulatory OX40-OX40L complex."
Structure 14:1321-1330(2006) [PubMed] [Europe PMC] [Abstract]