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Parathyroid Hormone (PTH)

iPTH; Intact Parathyroid Hormone; Parathormone; Parathyrin

Parathyroid hormone is secreted by the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium (Ca2+) in the blood, whereas calcitonin (a hormone produced by the parafollicular cells (C cells) of the thyroid gland) acts to decrease calcium concentration. PTH acts to increase the concentration of calcium in the blood by acting upon parathyroid hormone receptor in three parts of the body: PTH half-life is approximately 4 minutes. It has a molecular mass of 9.4 kDa.

PTH was one of the first hormones to be shown to use the G-protein, adenylyl cyclase second messenger system.Normal total plasma calcium level ranges from 8.5 to 10.2 mg/dL (2.12 mmol/L to 2.55 mmol/L).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V945Hu01 Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies MV945Hu22 Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
PV945Hu01 Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
LV945Hu71 Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V945Mu01 Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
PV945Mu01 Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V945Ra01 Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies MV945Ra21 Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
PV945Ra01 Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V945Ca01 Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies MV945Ca21 Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
PV945Ca01 Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V945Po01 Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies MV945Po21 Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
PV945Po01 Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
LV945Po71 Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
LV945Po81 FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V945Bo01 Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
PV945Bo01 Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V945Ga01 Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
PV945Ga01 Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
LV945Ga71 Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Parathyroid Hormone (PTH) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Parathyroid Hormone (PTH) Bioactivity
Antibodies NONE Monoclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Parathyroid Hormone (PTH) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Parathyroid Hormone (PTH) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Parathyroid Hormone (PTH) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Parathyroid Hormone (PTH) CLIA assay for Antigen Detection

Reference

"Nucleotide sequence of cloned cDNAs encoding human preproparathyroid hormone."
Proc. Natl. Acad. Sci. U.S.A. 78:7365-7369(1981) [PubMed] [Europe PMC] [Abstract]

"Nucleotide sequence of the human parathyroid hormone gene."
Proc. Natl. Acad. Sci. U.S.A. 80:2127-2131(1983) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Inefficient membrane targeting, translocation, and proteolytic processing by signal peptidase of a mutant preproparathyroid hormone protein."
J. Biol. Chem. 270:1629-1635(1995) [PubMed] [Europe PMC] [Abstract]

"Structural analysis of human proparathyroid hormone by a new microsequencing approach."
Nature 249:155-157(1974) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"The amino-acid sequence of the amino-terminal 37 residues of human parathyroid hormone."
Proc. Natl. Acad. Sci. U.S.A. 71:384-388(1974) [PubMed] [Europe PMC] [Abstract]

"Complete amino acid sequence of human parathyroid hormone."
Biochemistry 17:5723-5729(1978) [PubMed] [Europe PMC] [Abstract]

(In) Talmadge R.V., Owen M., Parsons J.A. (eds.);Calcium-regulating hormones, pp.9-14, Excerpta Medica Foundation, Amsterdam (1975)

"A reinvestigation of the amino-terminal sequence of human parathyroid hormone."
Biochemistry 14:1842-1847(1975) [PubMed] [Europe PMC] [Abstract]

"Solid-phase synthesis of the biologically active N-terminal 1-34 peptide of human parathyroid hormone."
Hoppe-Seyler's Z. Physiol. Chem. 355:415-421(1974) [PubMed] [Europe PMC] [Abstract]

"Synthesis of sequence 1-34 of human parathyroid hormone."
Helv. Chim. Acta 56:470-473(1973) [PubMed] [Europe PMC] [Abstract]

"Stimulation of glucose transport in osteoblastic cells by parathyroid hormone and insulin-like growth factor I."
Mol. Cell. Biochem. 348:33-42(2011) [PubMed] [Europe PMC] [Abstract]

"Investigation of the solution structure of the human parathyroid hormone fragment (1-34) by 1H NMR spectroscopy, distance geometry, and molecular dynamics calculations."
Biochemistry 30:6936-6942(1991) [PubMed] [Europe PMC] [Abstract]

"Stabilized NMR structure of human parathyroid hormone(1-34)."
Eur. J. Biochem. 215:315-321(1993) [PubMed] [Europe PMC] [Abstract]

"Structure of human parathyroid hormone 1-37 in solution."
J. Biol. Chem. 270:15194-15202(1995) [PubMed] [Europe PMC] [Abstract]

"Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37)."
Biochem. Biophys. Res. Commun. 267:213-220(2000) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution."
J. Biol. Chem. 275:27238-27244(2000) [PubMed] [Europe PMC] [Abstract]

"Molecular recognition of parathyroid hormone by its G protein-coupled receptor."
Proc. Natl. Acad. Sci. U.S.A. 105:5034-5039(2008) [PubMed] [Europe PMC] [Abstract]

"Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism."
J. Clin. Invest. 86:1084-1087(1990) [PubMed] [Europe PMC] [Abstract]

"A novel mutation of the signal peptide of the preproparathyroid hormone gene associated with autosomal recessive familial isolated hypoparathyroidism."
J. Clin. Endocrinol. Metab. 84:3792-3796(1999) [PubMed] [Europe PMC] [Abstract]

"Signal sequence mutation in autosomal dominant form of hypoparathyroidism induces apoptosis that is corrected by a chemical chaperone."
Proc. Natl. Acad. Sci. U.S.A. 104:19989-19994(2007) [PubMed] [Europe PMC] [Abstract]