Calcitonin Gene Related Peptide (CGRP)
CALCB; CGRP2; CALC2; CGRP-II; Calcitonin Gene Related Peptide 2; Calcitonin 2; Calcitonin Related Polypeptide Beta
CGRP is an important cutaneous neuropeptide. It is widely expressed in both the central and peripheral nervous system. CGRP is known as pro inflammatory factor and is thought to be involved in neurogenic inflammation. It was reported that CGRP stimulate the adhesiveness of human umbilical vein endothelial cells for monocytic cell line and neutrophils.The function of CGRP in skin remains unclear. However, evidences suggested that it may be directly involved in modulating the functions of keratinocytes, Langerhans cells and microvascular endothelial cells in the skin.On the other hand, psoriasis is generally known as inflammatory and proliferative skin disorder. In psoriatic plaque lesion there are epidermal influx of polymorphonulear leukocytes, and the presence of mononuclear infiltration in the papillary dermis and in the epidermis.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV935Hu01 | Recombinant Calcitonin Gene Related Peptide (CGRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV935Hu01 | Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IP. |
| PAV935Hu01 | Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV935Hu01 | CLIA Kit for Calcitonin Gene Related Peptide (CGRP) | CLIA assay for Antigen Detection |
| ELV935Hu01 | ELISA Kit for Calcitonin Gene Related Peptide (CGRP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV935Mu01 | Recombinant Calcitonin Gene Related Peptide (CGRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV935Mu01 | Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IP. |
| PAV935Mu01 | Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV935Mu01 | CLIA Kit for Calcitonin Gene Related Peptide (CGRP) | CLIA assay for Antigen Detection |
| ELV935Mu01 | ELISA Kit for Calcitonin Gene Related Peptide (CGRP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV935Ra01 | Recombinant Calcitonin Gene Related Peptide (CGRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV935Ra01 | Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IP. |
| PAV935Ra01 | Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV935Ra01 | CLIA Kit for Calcitonin Gene Related Peptide (CGRP) | CLIA assay for Antigen Detection |
| ELV935Ra01 | ELISA Kit for Calcitonin Gene Related Peptide (CGRP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV935Ca01 | Recombinant Calcitonin Gene Related Peptide (CGRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV935Ca01 | Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IP. |
| PAV935Ca01 | Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV935Ca01 | CLIA Kit for Calcitonin Gene Related Peptide (CGRP) | CLIA assay for Antigen Detection |
| ELV935Ca01 | ELISA Kit for Calcitonin Gene Related Peptide (CGRP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV935Po01 | Recombinant Calcitonin Gene Related Peptide (CGRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV935Po01 | Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IP. |
| PAV935Po01 | Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV935Po01 | CLIA Kit for Calcitonin Gene Related Peptide (CGRP) | CLIA assay for Antigen Detection |
| ELV935Po01 | ELISA Kit for Calcitonin Gene Related Peptide (CGRP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV935Bo01 | Recombinant Calcitonin Gene Related Peptide (CGRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV935Bo01 | Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IP. |
| PAV935Bo01 | Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV935Bo01 | CLIA Kit for Calcitonin Gene Related Peptide (CGRP) | CLIA assay for Antigen Detection |
| ELV935Bo01 | ELISA Kit for Calcitonin Gene Related Peptide (CGRP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV935Rb01 | Recombinant Calcitonin Gene Related Peptide (CGRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV935Rb01 | Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IP. |
| PAV935Rb01 | Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV935Rb01 | CLIA Kit for Calcitonin Gene Related Peptide (CGRP) | CLIA assay for Antigen Detection |
| ELV935Rb01 | ELISA Kit for Calcitonin Gene Related Peptide (CGRP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV935Mo01 | Recombinant Calcitonin Gene Related Peptide (CGRP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV935Mo01 | Monoclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IP. |
| PAV935Mo01 | Polyclonal Antibody to Calcitonin Gene Related Peptide (CGRP) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV935Mo01 | CLIA Kit for Calcitonin Gene Related Peptide (CGRP) | CLIA assay for Antigen Detection |
| ELV935Mo01 | ELISA Kit for Calcitonin Gene Related Peptide (CGRP) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Structure and expression of the human calcitonin/CGRP genes."
FEBS Lett. 209:97-103(1986) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"A second human calcitonin/CGRP gene."
FEBS Lett. 183:403-407(1985) [PubMed] [Europe PMC] [Abstract]
"Identification in the human central nervous system, pituitary, and thyroid of a novel calcitonin gene-related peptide, and partial amino acid sequence in the spinal cord."
J. Biol. Chem. 262:542-545(1987) [PubMed] [Europe PMC] [Abstract]
"Isolation, purification and characterization of beta-hCGRP from human spinal cord."
Biochem. Biophys. Res. Commun. 167:993-1000(1990) [PubMed] [Europe PMC] [Abstract]
"Isolation and characterization of peptides which act on rat platelets, from a pheochromocytoma."
Biochem. Biophys. Res. Commun. 185:134-141(1992) [PubMed] [Europe PMC] [Abstract]