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Pyruvate Dehydrogenase Phosphatase (PDP)
Pyruvate Dehydrogenase Phosphatase (PDP)
PDP1; PDH; PPM2C; Protein Phosphatase 2C Magnesium-Dependent Catalytic Subunit; Pyruvate Dehyrogenase Phosphatase Catalytic Subunit 1
Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic PPM2C is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
V924Mu01
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
PV924Mu01
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pyruvate Dehydrogenase Phosphatase (PDP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pyruvate Dehydrogenase Phosphatase (PDP) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pyruvate Dehydrogenase Phosphatase (PDP) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pyruvate Dehydrogenase Phosphatase (PDP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pyruvate Dehydrogenase Phosphatase (PDP) CLIA assay for Antigen Detection
Reference
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"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Lysine acetylation targets protein complexes and co-regulates major cellular functions." Science 325:834-840(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Pyruvate dehydrogenase phosphatase deficiency: identification of the first mutation in two brothers and restoration of activity by protein complementation." J. Clin. Endocrinol. Metab. 90:4101-4107(2005) [PubMed ] [Europe PMC ] [Abstract ]