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Ceruloplasmin (CP)

CP2; CER; Caeruloplasmin; Ferroxidase; Oxygen Oxidoreductase

Ceruloplasmin is is the major copper-carrying protein in the blood, and in addition plays a role in iron metabolism. It was first described in 1948.  It is an enzyme (EC 1.16.3.1) synthesized in the liver containing 6 atoms of copper in its structure. Ceruloplasmin carries 90% of the copper in plasma. The other 10% is carried by albumin, albumin may be confused at times to have a greater importance as a copper carrier because it binds copper less tightly than ceruloplasmin. Ceruloplasmin exhibits a copper-dependent oxidase activity, which is associated with possible oxidation of Fe2 (ferrous iron) into Fe3 (ferric iron), therefore assisting in its transport in the plasma in association with transferrin, which can only carry iron in the ferric state. The molecular weight of human ceruloplasmin is reported to be 151kDa.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V902Hu01 Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies MV902Hu22 Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
PV902Hu01 Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
LV902Hu71 Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits KEV902Hu ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
KCV902Hu CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V902Mu01 Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
PV902Mu01 Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits KEV902Mu ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V902Ra01 Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies MV902Ra21 Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
PV902Ra01 Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits KEV902Ra ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
KCV902Ra CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ceruloplasmin (CP) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ceruloplasmin (CP) Bioactivity
Antibodies NONE Monoclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ceruloplasmin (CP) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ceruloplasmin (CP) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ceruloplasmin (CP) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ceruloplasmin (CP) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ceruloplasmin (CP) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ceruloplasmin (CP) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ceruloplasmin (CP) CLIA assay for Antigen Detection

Reference

"Complete cDNA sequence of human preceruloplasmin."
Proc. Natl. Acad. Sci. U.S.A. 83:5086-5090(1986) [PubMed] [Europe PMC] [Abstract]

"Fine structure of the human ceruloplasmin gene."
Biochem. Biophys. Res. Commun. 208:1028-1035(1995) [PubMed] [Europe PMC] [Abstract]

"Isolation of a human ceruloplasmin cDNA clone that includes the N-terminal leader sequence."
FEBS Lett. 203:185-190(1986) [PubMed] [Europe PMC] [Abstract]

"Characterization, mapping, and expression of the human ceruloplasmin gene."
Proc. Natl. Acad. Sci. U.S.A. 83:3257-3261(1986) [PubMed] [Europe PMC] [Abstract]

"Single-chain structure of human ceruloplasmin: the complete amino acid sequence of the whole molecule."
Proc. Natl. Acad. Sci. U.S.A. 81:390-394(1984) [PubMed] [Europe PMC] [Abstract]

"Internal triplication in the structure of human ceruloplasmin."
Proc. Natl. Acad. Sci. U.S.A. 80:115-119(1983) [PubMed] [Europe PMC] [Abstract]

"Complete amino acid sequence of a 50,000-dalton fragment of human ceruloplasmin."
Proc. Natl. Acad. Sci. U.S.A. 78:790-794(1981) [PubMed] [Europe PMC] [Abstract]

"Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. I. Amino acid sequence of the cyanogen bromide peptides."
J. Biol. Chem. 255:2878-2885(1980) [PubMed] [Europe PMC] [Abstract]

"Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. II. Amino acid sequence of the tryptic peptides."
J. Biol. Chem. 255:2886-2896(1980) [PubMed] [Europe PMC] [Abstract]

"Human ceruloplasmin. Tissue-specific expression of transcripts produced by alternative splicing."
J. Biol. Chem. 265:10780-10785(1990) [PubMed] [Europe PMC] [Abstract]

"Ceruloplasmin metabolism and function."
Annu. Rev. Nutr. 22:439-458(2002) [PubMed] [Europe PMC] [Abstract]

"A proteomic analysis of human bile."
Mol. Cell. Proteomics 3:715-728(2004) [PubMed] [Europe PMC] [Abstract]

"Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
Proteomics 4:454-465(2004) [PubMed] [Europe PMC] [Abstract]

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

"Enrichment of glycopeptides for glycan structure and attachment site identification."
Nat. Methods 6:809-811(2009) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"The X-ray structure of human serum ceruloplasmin at 3.1 A: nature of the copper centres."
J. Biol. Inorg. Chem. 1:15-23(1996)

"Ceruloplasmin revisited: structural and functional roles of various metal cation-binding sites."
Acta Crystallogr. D 63:240-248(2007) [PubMed] [Europe PMC] [Abstract]

"Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease."
Neurology 63:1912-1917(2004) [PubMed] [Europe PMC] [Abstract]

"Functional relevance of ceruloplasmin mutations in Parkinson's disease."
FASEB J. 19:1851-1853(2005) [PubMed] [Europe PMC] [Abstract]