Podocin (PDCN)
NPHS2; NPHS-2; Nephrosis 2; Idiopathic Steroid-Resistant
Podocin is a protein which lines the podocytes and assists in maintaining the barrier at the glomerular basement membrane.NPHS2 encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN).
SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V873Hu01 | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | MV873Hu22 | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| PV873Hu01 | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| LV873Hu71 | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| LV873Hu81 | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV873Hu | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| PV873Mu01 | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| LV873Mu71 | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV873Mu | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | V873Ra01 | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| PV873Ra01 | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| LV873Ra71 | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEV873Ra | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Podocin (PDCN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Podocin (PDCN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Podocin (PDCN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Podocin (PDCN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Podocin (PDCN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Podocin (PDCN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Podocin (PDCN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Podocin (PDCN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Podocin (PDCN) | CLIA assay for Antigen Detection |
Reference
"NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome."
Nat. Genet. 24:349-354(2000) [PubMed] [Europe PMC] [Abstract]
Erratum
Nat. Genet. 25:125-125(2000) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Interaction with podocin facilitates nephrin signaling."
J. Biol. Chem. 276:41543-41546(2001) [PubMed] [Europe PMC] [Abstract]
"Characterization of a short isoform of the kidney protein podocin in human kidney."
BMC Nephrol. 14:102-102(2013) [PubMed] [Europe PMC] [Abstract]
"NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele."
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