Pre-B-Lymphocyte Gene 1 (VPREB1)
CD179A; IGVPB; VPREB; IGI; Immunoglobulin Iota Chain; CD179 antigen-like family member A; Protein VPreB1; V(pre)B protein
CD179a (VpreB) is a 126 aa-long polypeptide with apparent MW of 16-18 kDa. It is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. CD179a has an Ig V domain-like structure, but lacks the last beta-strand (beta7) of a typical V domain. Instead, it has a carboxyl terminal end that shows no sequence homologies to any other proteins.
CD179a associates non-covalently with CD179b (lambda5 or lambda-like) carrying an Ig C domain-like structure to form an Ig light chain-like structure, which is called the surrogate light chain or pseudo light chain. In this complex, the incomplete V domain of CD179a appears to be complemented by the extra beta7 strand of CD179b.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV869Hu01 | Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV869Hu01 | Monoclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IP. |
| PAV869Hu01 | Polyclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV869Hu01 | CLIA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | CLIA assay for Antigen Detection |
| ELV869Hu01 | ELISA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV869Mu01 | Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV869Mu01 | Monoclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IP. |
| PAV869Mu01 | Polyclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV869Mu01 | CLIA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | CLIA assay for Antigen Detection |
| ELV869Mu01 | ELISA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV869Ra01 | Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV869Ra01 | Monoclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IP. |
| PAV869Ra01 | Polyclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV869Ra01 | CLIA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | CLIA assay for Antigen Detection |
| ELV869Ra01 | ELISA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV869Ca01 | Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV869Ca01 | Monoclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IP. |
| PAV869Ca01 | Polyclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV869Ca01 | CLIA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | CLIA assay for Antigen Detection |
| ELV869Ca01 | ELISA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV869Po01 | Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV869Po01 | Monoclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IP. |
| PAV869Po01 | Polyclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV869Po01 | CLIA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | CLIA assay for Antigen Detection |
| ELV869Po01 | ELISA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV869Bo01 | Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV869Bo01 | Monoclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IP. |
| PAV869Bo01 | Polyclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV869Bo01 | CLIA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | CLIA assay for Antigen Detection |
| ELV869Bo01 | ELISA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV869Rb01 | Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV869Rb01 | Monoclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IP. |
| PAV869Rb01 | Polyclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV869Rb01 | CLIA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | CLIA assay for Antigen Detection |
| ELV869Rb01 | ELISA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPV869Mo01 | Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAV869Mo01 | Monoclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IP. |
| PAV869Mo01 | Polyclonal Antibody to Pre-B-Lymphocyte Gene 1 (VPREB1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLV869Mo01 | CLIA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | CLIA assay for Antigen Detection |
| ELV869Mo01 | ELISA Kit for Pre-B-Lymphocyte Gene 1 (VPREB1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
"Structure and pre-B lymphocyte restricted expression of the VpreB in humans and conservation of its structure in other mammalian species."
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BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
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Science 316:291-294(2007) [PubMed] [Europe PMC] [Abstract]
"Engineering and characterization of a single chain surrogate light chain variable domain."
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