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ATP Binding Cassette Transporter G2 (ABCG2)

CDw338; CD338; ABC-G2; MRX; BCRP1; ABC15; ABCP; BCRP; BMDP; MXR; MXR1; Mitoxantrone resistance-associated protein; Breast Cancer Resistance Protein 1; Urate exporter

ATP-binding cassette, sub-family G (WHITE), member 2 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V851Hu01 Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies MV851Hu22 Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
PV851Hu01 Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits KEV851Hu ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins V851Mu01 Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
PV851Mu01 Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits KEV851Mu ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits KEV851Ra ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant ATP Binding Cassette Transporter G2 (ABCG2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native ATP Binding Cassette Transporter G2 (ABCG2) Bioactivity
Antibodies NONE Monoclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to ATP Binding Cassette Transporter G2 (ABCG2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for ATP Binding Cassette Transporter G2 (ABCG2) CLIA assay for Antigen Detection

Reference

"A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance."
Cancer Res. 58:5337-5339(1998) [PubMed] [Europe PMC] [Abstract]

"A multidrug resistance transporter from human MCF-7 breast cancer cells."
Proc. Natl. Acad. Sci. U.S.A. 95:15665-15670(1998) [PubMed] [Europe PMC] [Abstract]

Erratum
Proc. Natl. Acad. Sci. U.S.A. 96:2569-2569(1999)

"Identification of breast cancer resistant protein/mitoxantrone resistance/placenta-specific, ATP-binding cassette transporter as a transporter of NB-506 and J-107088, topoisomerase I inhibitors with an indolocarbazole structure."
Cancer Res. 61:2827-2832(2001) [PubMed] [Europe PMC] [Abstract]

"The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype."
Nat. Med. 7:1028-1034(2001) [PubMed] [Europe PMC] [Abstract]

"The expression and functional characterization of ABCG2 in brain endothelial cells and vessels."
FASEB J. 17:2085-2087(2003) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes."
Cancer Res. 59:8-13(1999) [PubMed] [Europe PMC] [Abstract]

"Role of ABCG1 and other ABCG family members in lipid metabolism."
J. Lipid Res. 42:1513-1520(2001) [PubMed] [Europe PMC] [Abstract]

"Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2."
J. Biol. Chem. 279:19781-19789(2004) [PubMed] [Europe PMC] [Abstract]

"N-linked glycosylation of the human ABC transporter ABCG2 on asparagine 596 is not essential for expression, transport activity, or trafficking to the plasma membrane."
Biochemistry 44:5420-5429(2005) [PubMed] [Europe PMC] [Abstract]

"Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition."
Biochim. Biophys. Acta 1668:53-63(2005) [PubMed] [Europe PMC] [Abstract]

"Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2."
J. Cell Sci. 118:1417-1426(2005) [PubMed] [Europe PMC] [Abstract]

"Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein."
J. Biol. Chem. 282:27841-27846(2007) [PubMed] [Europe PMC] [Abstract]

"Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study."
Lancet 372:1953-1961(2008) [PubMed] [Europe PMC] [Abstract]

"Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout."
Proc. Natl. Acad. Sci. U.S.A. 106:10338-10342(2009) [PubMed] [Europe PMC] [Abstract]

"Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population."
Sci. Transl. Med. 1:5ra11-5ra11(2009) [PubMed] [Europe PMC] [Abstract]

"ABCG2 transports and transfers heme to albumin through its large extracellular loop."
J. Biol. Chem. 285:33123-33133(2010) [PubMed] [Europe PMC] [Abstract]

"ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans."
Nucleosides Nucleotides Nucleic Acids 30:1091-1097(2011) [PubMed] [Europe PMC] [Abstract]

"Human ABCG2: structure, function, and its role in multidrug resistance."
Int. J. Biochem. Mol. Biol. 3:1-27(2012) [PubMed] [Europe PMC] [Abstract]

"ABCG2 null alleles define the Jr(a-) blood group phenotype."
Nat. Genet. 44:131-132(2012) [PubMed] [Europe PMC] [Abstract]

"Null alleles of ABCG2 encoding the breast cancer resistance protein define the new blood group system Junior."
Nat. Genet. 44:174-177(2012) [PubMed] [Europe PMC] [Abstract]

"Mitochondrial localization of ABC transporter ABCG2 and its function in 5-aminolevulinic acid-mediated protoporphyrin IX accumulation."
PLoS ONE 7:E50082-E50082(2012) [PubMed] [Europe PMC] [Abstract]

"Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8."
J. Hum. Genet. 47:285-310(2002) [PubMed] [Europe PMC] [Abstract]

"Eight novel single nucleotide polymorphisms in ABCG2/BCRP in Japanese cancer patients administered irinotacan."
Drug Metab. Pharmacokinet. 18:212-217(2003) [PubMed] [Europe PMC] [Abstract]

"Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine."
Pharmacogenetics 13:19-28(2003) [PubMed] [Europe PMC] [Abstract]

"Single nucleotide polymorphisms modify the transporter activity of ABCG2."
Cancer Chemother. Pharmacol. 56:161-172(2005) [PubMed] [Europe PMC] [Abstract]

"Genetic variation and haplotype structure of the ABC transporter gene ABCG2 in a Japanese population."
Drug Metab. Pharmacokinet. 21:109-121(2006) [PubMed] [Europe PMC] [Abstract]