Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. Its main effect is the slowing down of fibrinolysis, the process that leads to the breakdown of blood clots. The aim in its use is to decrease the need for blood transfusions during surgery, as well as end-organ damage due to hypotension (low blood pressure) as a result of marked blood loss. The drug was temporarily withdrawn worldwide in 2007 after studies suggested that its use increased the risk of complications or death; this was confirmed by follow-up studies.
Aprotinin is a monomeric (single-chain) globular polypeptide derived from bovine lung tissue; it has a molecular weight of 6512 and consists of 16 different amino acids arranged in a chain of 58 amino acid residues.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV844Hu01
Recombinant Aprotinin (AP)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV844Hu01
Monoclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IP.
PAV844Hu01
Polyclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IF.
Assay Kits
CLV844Hu01
CLIA Kit for Aprotinin (AP)
CLIA assay for Antigen Detection
ELV844Hu01
ELISA Kit for Aprotinin (AP)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV844Mu01
Recombinant Aprotinin (AP)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV844Mu01
Monoclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IP.
PAV844Mu01
Polyclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IF.
Assay Kits
CLV844Mu01
CLIA Kit for Aprotinin (AP)
CLIA assay for Antigen Detection
ELV844Mu01
ELISA Kit for Aprotinin (AP)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV844Ra01
Recombinant Aprotinin (AP)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV844Ra01
Monoclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IP.
PAV844Ra01
Polyclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IF.
Assay Kits
CLV844Ra01
CLIA Kit for Aprotinin (AP)
CLIA assay for Antigen Detection
ELV844Ra01
ELISA Kit for Aprotinin (AP)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV844Ca01
Recombinant Aprotinin (AP)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV844Ca01
Monoclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IP.
PAV844Ca01
Polyclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IF.
Assay Kits
CLV844Ca01
CLIA Kit for Aprotinin (AP)
CLIA assay for Antigen Detection
ELV844Ca01
ELISA Kit for Aprotinin (AP)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV844Po01
Recombinant Aprotinin (AP)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV844Po01
Monoclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IP.
PAV844Po01
Polyclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IF.
Assay Kits
CLV844Po01
CLIA Kit for Aprotinin (AP)
CLIA assay for Antigen Detection
ELV844Po01
ELISA Kit for Aprotinin (AP)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV844Bo01
Recombinant Aprotinin (AP)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV844Bo01
Monoclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IP.
PAV844Bo01
Polyclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IF.
Assay Kits
CLV844Bo01
CLIA Kit for Aprotinin (AP)
CLIA assay for Antigen Detection
ELV844Bo01
ELISA Kit for Aprotinin (AP)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV844Rb01
Recombinant Aprotinin (AP)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV844Rb01
Monoclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IP.
PAV844Rb01
Polyclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IF.
Assay Kits
CLV844Rb01
CLIA Kit for Aprotinin (AP)
CLIA assay for Antigen Detection
ELV844Rb01
ELISA Kit for Aprotinin (AP)
Enzyme-linked immunosorbent assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
RPV844Mo01
Recombinant Aprotinin (AP)
Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies
MAV844Mo01
Monoclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IP.
PAV844Mo01
Polyclonal Antibody to Aprotinin (AP)
WB; IHC; ICC; IF.
Assay Kits
CLV844Mo01
CLIA Kit for Aprotinin (AP)
CLIA assay for Antigen Detection
ELV844Mo01
ELISA Kit for Aprotinin (AP)
Enzyme-linked immunosorbent assay for Antigen Detection
Reference
"Purification and characterization of aprotinin from porcine lungs." Biotechnol. Lett. 0:0-0(2008).
